Burden and predictors of 30- and 90-day readmission in patients with aortic dissection: A nationwide retrospective analysis

Authors

• Adeena Jamil, Nishtar Medical University, Pakistan
• Eliza Aisha, Dow University of Health Sciences, Pakistan
• Muhammad Furqan, King Edward Medical University, Pakistan
• Muhammad Hashim Akram, Chughtai Lab, Pakistan
• Saira Khan, Changsha Medical University, China
• Ahmed Hasan, Jinnah Sindh Medical University, Pakistan
• Sharib Afzal Bughio, Ziauddin Medical University, Pakistan
• Muhammad Adil Areeb, Avicenna Tajik State Medical University, Tajikistan
• Alveena Zafar, Aga Khan University
• Muhammad Waqas Ali, Lahore General Hospital, Pakistan

Document Type

Article

Department

Medicine; Medical College Pakistan

Abstract

Aortic dissection (AD) is a life-threatening emergency, with type A requiring surgery and type B generally managed medically. This retrospective cohort study analyzed 30- and 90-day readmission rates using data from the 2016-2017 Nationwide Readmissions Database. Adult patients (≥18 years) with a principal diagnosis of AD were identified by International Classification of Diseases-10th Revision-Clinical Modification codes. Outcomes included 30- and 90-day all-cause readmissions, mortality, length of stay, charges, and causes of readmission. Among 26,477 index admissions, in-hospital mortality was 12.70%. Of the 23,117 survivors, and 11.92% were readmitted within 30 days. Among 21,421 index admissions, in-hospital mortality was 12.57%, and 14.92% were readmitted within 30 days. Readmitted patients were younger and more likely to be insured by Medicaid or Medicare; chronic pulmonary disease and renal failure were the strongest comorbidity signals. In regression models, Medicaid (odds ratio [OR] 1.23-1.36) and Medicare (OR 1.20-1.29), as well as chronic pulmonary disease (OR 1.29-1.34) and renal failure (OR 1.32-1.36), were independently associated with increased risk of readmission. At the same time, older age was associated with a slight reduction (OR 0.99 per year). Hospital factors, sex, and most other comorbidities were not significant. Readmission stays averaged about 6 days, with charges ranging from $99,000 to $106,000. In-hospital mortality was 3%, which is lower than the index mortality rate. Readmissions after AD are frequent and resource-intensive, particularly within 90 days. Extending follow-up and focusing on high-risk groups, such as Medicaid/Medicare patients and those with pulmonary or renal disease, may help reduce this burden.

Comments

Volume, Issue and Pagination was not provided by author/publisher.

Publication (Name of Journal)

Cardiology in review

DOI

10.1097/CRD.0000000000001304

Recommended Citation

Jamil, A., Aisha, E., Furqan, M., Akram, M. H., Khan, S., Hasan, A., Bughio, S. A., Areeb, M. A., Zafar, A., Ali, M. W. (2026). Burden and predictors of 30- and 90-day readmission in patients with aortic dissection: A nationwide retrospective analysis. Cardiology in review.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_mc/672