Racial and ethnic disparities in utilization of mechanical circulatory support for cardiogenic shock following acute myocardial infarction: A retrospective cross-sectional study

Document Type

Article

Department

Medical College Pakistan

Abstract

Background: Mechanical circulatory support (MCS) is critical in the management of cardiogenic shock (CS) complicating acute myocardial infarction (AMI), but racial/ethnic disparities in MCS utilization remain understudied.
Methods: We extracted data from the National Inpatient Sample database for the years 2018 to 2020. Patients aged ≥18 years with AMI and CS listed as primary or secondary diagnosis were identified using ICD-10-CM. The primary outcome was in-hospital mortality. Secondary outcomes included MCS utilization, hospital length of stay (LOS), total hospital charges, acute kidney injury (AKI)/hemodialysis, and sepsis. Multivariable logistic and linear regression models were used to assess associations between race/ethnicity and in-hospital outcomes.
Results: Among 89 125 hospitalizations for AMI and CS, Hispanics had lower in-hospital mortality than Whites (OR 0.86; 95% CI, 0.76-0.96). The MCS use was higher among Asians or Pacific Islanders (OR 1.35; 95% CI, 1.14-1.60) and Hispanics (OR 1.15; 95% CI, 1.01-1.30) than among Whites. Hispanics had longer LOS (β = 1.3 days; 95% CI, 0.78-1.7), whereas Blacks had shorter stays (β = -0.50 days; 95% CI,-0.91 to -0.10) than Whites. The rates of AKI/hemodialysis were higher among Hispanics (OR 1.26; 95% CI, 1.12-1.42), Blacks (OR 1.59; 95% CI, 1.40-1.79), and Asians or Pacific Islanders (OR 1.39; 95% CI, 1.18-1.64) than Whites. Sepsis rate was greater among Hispanics (OR 1.18; 95% CI, 1.04-1.34). Total hospital charges were higher among Hispanics ($53 770; 95% CI, $39 307-$68 233) and Asians or Pacific Islanders ($33 737; 95% CI, $8954-$58 520), than Whites.
Conclusion: Racial and ethnic disparities in MCS use and clinical outcomes persist among patients with AMI and CS.

Publication (Name of Journal)

Annals of Medicine and Surgery

DOI

10.1097/MS9.0000000000004407

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