Differences in cardiometabolic risk between insulin-sensitive and insulin-resistant overweight and obese children
Document Type
Article
Department
Family Medicine
Abstract
Background: It is known that 15-30% overweight/obese adults do not suffer cardiometabolic consequences. There is limited literature examining factors that can be used to assess cardiometabolic health in overweight/obese children. If such factors can be identified, they would aid in differentiating those most in need for aggressive management.
Methods: Baseline data from 7- to 12-year-old, overweight, and obese children enrolled in a weight management program at an urban hospital were analyzed. Homeostatic model assessment for insulin resistance (HOMA-IR) Results: Of the 362 overweight/obese participants, 157 (43.5%) were insulin sensitive and 204 (56.5%) were insulin resistant. Compared to the insulin-sensitive group, the insulin-resistant group was older (8.6±1.6 vs. 9.9±1.7; pResults: Using a HOMA-IR value of ≥2.6, clinical providers can identify prepubertal and early pubertal children most at risk. Focusing limited resources on aggressive weight interventions may lead to improvement in cardiometabolic health.
Publication ( Name of Journal)
Childhood Obesity
Recommended Citation
Khan, U. I.,
McGinn, A. P.,
Isasi, C. R.,
Groisman-Perelstein, A.,
Ginsberg, M.,
Wylie-Rosett, J.
(2015). Differences in cardiometabolic risk between insulin-sensitive and insulin-resistant overweight and obese children. Childhood Obesity, 11(3), 289-296.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_fam_med/197
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Comments
This work was published before the author joined Aga Khan University.