Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan.

Authors

Fujio Kayama, Jichi Medical University, Shimono, Tochigi, Japan
Zafar Fatmi, Aga Khan UniversityFollow
Akihiko Ikegami, Jichi Medical University, Shimono, Tochigi, Japan
Atsuko Mizuno, Jichi Medical University, Shimono, Tochigi, Japan
Mayumi Ohtsu, Jichi Medical University, Shimono, Tochigi, Japan
Nathern Mise, Jichi Medical University, Shimono, Tochigi, Japan
Xiaoyi Cui, Jichi Medical University, Shimono, Tochigi, Japan
Masanori Ogawa, Jichi Medical University, Shimono, Tochigi, Japan
Takako Sakamoto, Jichi Medical University, Shimono, Tochigi, Japan
Yoshiko Nakagi, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
Takahiko Yoshida, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
Ambreen Sahito, Aga Khan University
Shahla Naeem, Aga Khan UniversityFollow
Kulsoom Ghias, Aga Khan UniversityFollow
Hina Saeed Zuberi, Aga Khan UniversityFollow
Kanwal Tariq, Aga Khan University
Yayoi Kobayashi, National Institute of Environmental Studies, Tsukuba, Ibaraki, Japan
Keiko Nohara, National Institute of Environmental Studies, Tsukuba, Ibaraki, Japan

Document Type

Article

Department

Community Health Sciences

Abstract

AIM:

Exposure assessment of lead (Pb) and Arsenic (As) from food, water, and house dust intake were assessed among pregnant women, their children and fetuses in Pakistan and Japan, as well as their body burden of the metals in their blood.

METHOD:

Fifty families which included a pregnant woman, a fetus and the 1-3-year-old siblings were recruited in Karachi and Khairpur in Pakistan, and Shimotsuke and Asahikawa in Japan, respectively. Their dietary exposure to Pb and As was measured in 3-day food duplicates and drinking water by ICP-MP. Pb in house dust and respirable dust was evaluated with an energy dispersive X-ray fluorescence spectrometry. Non-radioactive isotope Pb profiles of blood specimens will be compared with those of the exposure origins, such as food duplicates, respirable house dust, the soils nearby, and gasoline.

RESULTS:

Judging from the data collected and analyzed so far, contribution from dietary intake is highly correlated to higher body burden of Pb among Pakistani mothers. Additional data analyses will reveal the status of Pb and As body burden in Pakistani mothers, fetuses and their siblings, and causal sources of high body burden is delineated by Pb isotope profile analysis of different sources of Pb exposure.

Publication (Name of Journal)

Reviews on Environmental Health

Recommended Citation

Kayama, F., Fatmi, Z., Ikegami, A., Mizuno, A., Ohtsu, M., Mise, N., Cui, X., Ogawa, M., Sakamoto, T., Nakagi, Y., Yoshida, T., Sahito, A., Naeem, S., Ghias, K., Zuberi, H. S., Tariq, K., Kobayashi, Y., Nohara, K. (2016). Exposure assessment of lead from food and airborne dusts and biomonitoring in pregnant mothers, their fetus and siblings in Karachi, Pakistan and Shimotsuke, Japan.. Reviews on Environmental Health, 31(1), 33-35.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_chs_chs/292