Docking prediction of levodopa in the receptor binding domain of spike protein of SARS-CoV-2

Authors

Abdul Mannan Baig, Aga Khan UniversityFollow
Areeba Khaleeq, Aga Khan UniversityFollow
Hira Syeda, Mohammad Ali Jinnah University, Karachi, Pakistan
Noor Bibi, Luther College, United States

Document Type

Article

Department

Biological and Biomedical Sciences

Abstract

Levodopa is a prodrug that is converted into dopamine, which replenishes the deficient dopamine in the brain of patients suffering from Parkinsonism. We hypothesize that levodopa may interact with the receptor binding domain of the SARS-CoV-2 and may act as a physical impediment to the viral entry into the host cell.

Publication (Name of Journal)

ACS Pharmacology & Translational Science

Recommended Citation

Baig, A. M., Khaleeq, A., Syeda, H., Bibi, N. (2021). Docking prediction of levodopa in the receptor binding domain of spike protein of SARS-CoV-2. ACS Pharmacology & Translational Science, 4(1), 406-409.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_bbs/904