Title

Docking prediction of amantadine in the receptor binding domain of spike protein of SARS-CoV-2

Document Type

Article

Department

Biological and Biomedical Sciences

Abstract

Amantadine has recently been shown to improve patients with COVID-19. In addition to its known mechanism of actions, we performed docking prediction of this drug on the receptor-binding domain of severe acute respiratory syndrome coronavirus 2, SARS-CoV-2. We hypothesize that such interaction may possibly have contributed a role in the clinical improvements reported.

Publication

ACS Pharmacology & Translational Science

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