Docking prediction of amantadine in the receptor binding domain of spike protein of SARS-CoV-2
Biological and Biomedical Sciences
Amantadine has recently been shown to improve patients with COVID-19. In addition to its known mechanism of actions, we performed docking prediction of this drug on the receptor-binding domain of severe acute respiratory syndrome coronavirus 2, SARS-CoV-2. We hypothesize that such interaction may possibly have contributed a role in the clinical improvements reported.
Publication ( Name of Journal)
ACS Pharmacology & Translational Science
Baig, A. M.,
(2020). Docking prediction of amantadine in the receptor binding domain of spike protein of SARS-CoV-2. ACS Pharmacology & Translational Science, 3(6), 1430-1433.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_bbs/891