Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh.
Document Type
Article
Department
Biological and Biomedical Sciences
Abstract
In continuation of our work on Indian celery (Seseli diffusum (Roxb. ex Sm.) Santapau & Wagh, Umbelliferae), the fractionation of the 80% MeOHH2O extract of the seeds was performed to identify the principles responsible for its folk use as an antispasmodic and diuretic. Several compounds were isolated as active components: seselin (1) and anthriscinol methyl ether (4) showed a selective cytotoxicity to some yeast strains. Compound 1 also showed spasmolytic activity. On the other hand, isopimpinellin (3) and isorutarin (5) exhibited a spasmogenic effect on the smooth muscle preparations. Compound 5 was also found to have antioxidant activity. Among them, compound 4 was isolated for the first time from this plant.
Publication (Name of Journal)
Phytotherapy Research
Recommended Citation
Abbaskhan, A.,
Choudhary, M.,
Ghayur, M.,
Parween, Z.,
Shaheen, F.,
Gilani, A.,
Maruyama, T.,
Iqbal, K.,
Tsuda, Y.
(2012). Biological activities of Indian celery, Seseli diffusum (Roxb. ex Sm.) Sant. & Wagh.. Phytotherapy Research, 26(5), 783-786.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_bbs/46