Title
Emerging Insights for Better Delivery of Chemicals and Stem Cells to the Brain.
Document Type
Article
Department
Biological and Biomedical Sciences
Publication ( Name of Journal)
ACS chemical neuroscience
Recommended Citation
Baig, A. M.
(2017). Emerging Insights for Better Delivery of Chemicals and Stem Cells to the Brain.. ACS chemical neuroscience, 8(6), 1119-1121.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_bbs/302
Comments
The human central nervous system and its vascularity has evolved a complex yet useful barricade, called the blood-brain barrier. The understanding of this barrier and the transport proteins that allow a selective access across it remains fundamental in designing chemicals and molecules that could cross it and prove therapeutically beneficial. After the recent findings of the brain-lymphatic link and the movement of chemical molecules from the central nervous system into general circulation, the model of the blood-brain barrier needs to be revisited. Here the author intends to discuss the components of the blood-brain barrier, debate the novel routes of administration and delivery systems for the drugs and embryonic stem cells that could cross or bypass the blood-brain barrier in order to reach the central nervous system.