Factors associated with preterm premature rupture of membranes: A case-control study in a tertiary hospital in Kabul, Afghanistan

AKU Student

no

Authors

• Atia Sharif Nadi, Cure hospital, fistula surgery, Kabul
• Freshta Sharif tawakkuli, Cure hospital, fistula surgery, Kabul
• Zainab Sharif Ezadi, Cure hospital, fistula surgery, Kabul
• Sayed Murtaza Sadat Hofiani, Afghanistan Center for Translational Medicine and Public Health (ACTMPH), Kabul
• Shoaib Murtaza Sadat Naeemi, Afghanistan Center for Translational Medicine and Public Health (ACTMPH), Kabul
• Ahmad Komail Frogh, Afghanistan Center for Translational Medicine and Public Health (ACTMPH), Kabul

Document Type

Article

DOI

10.71071/JAM/v12i2.1.14a

Abstract

Background: It is essential to identify preterm premature rupture of membranes (PPROM) and its associated risk factors to reduce its impact. This study aims to find the demographic, reproductive, and obstetric factors associated with PPROM among women in Kabul, Afghanistan.
Methods: This case-control study was conducted over six months in 2023 at a tertiary hospital in Kabul, Afghanistan. We included 40 cases of PPROM and 80 controls without PPROM in this study. We used structured questionnaires to collect demographic, reproductive, and obstetric characteristics of the participants. To find the factors associated with PPROM, Logistic regression was performed using IBM SPSS V21.0.
Results: The majority of PPROM case were in the 20-29 year age group, accounting for 63.9%. Lack of antenatal care (ANC) follow-up was significantly linked to a higher risk of PPROM (AOR = 4.16, 95% CI: 1.13 – 15.36, p=0.032). The presence of a urinary tract infection was the most significant predictor of PPROM (AOR =18.25, 95% CI: 3.60 – 92.52, p< 0.001). The study did not find a significant link between anemia, renal disorder, and diabetes with PPROM.
Conclusion: lack of ANC follow-up and suffering from urinary tract infections (UTIs) were identified as risk factors for PPROM in this study. Improving antenatal care follow-up and addressing urinary tract infections during pregnancy could potentially lower the incidence of PPROM. More research is needed to investigate additional factors contributing to PPROM in different settings.

Recommended Citation

Nadi, A S, tawakkuli, F S, Ezadi, Z S, Hofiani, S M, Naeemi, S M, & Frogh, A K. Factors associated with preterm premature rupture of membranes: A case-control study in a tertiary hospital in Kabul, Afghanistan. Journal of Asian Midwives. 2025;12(2):26–39.