The Aga Khan University has established the Institute for Global Health and Development to drive collaboration across the University’s multi-country campuses, connect academic entities, compete for large-scale grants, and undertake interdisciplinary research and related programming.

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Submissions from 2024

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Zinc supplementation for acute and persistent watery diarrhoea in children: A systematic review and meta-analysis, Ayesha Arshad Ali, Syeda Kanza Naqvi, Zain Hasnain, Mustafa Bin Ali Zubairi, Ashraf Sharif, Rehana Abdus Salam, Sajid Bashir Soofi, Shabina Ariff, Yasir Bin Nisar, and Jai K. Das

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Effect of maternal and newborn care service package on perinatal and newborn mortality: A cluster randomized clinical trial, Shabina Ariff, Uswa Jiwani, Arjumand Rizvi, Sajid Muhammad, A Hussain, Imran Ahmed, Masawar Hussain, Muhammad Usman, Junaid Iqbal, Zahid Memon, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Reporting of equity in observational epidemiology: A methodological review, Omar Dewidar, Ali Al-Zubaidi, Mostafa Bondok, Leenah Abdelrazeq, Jimmy Huang, Alyssa Jearvis, Lucy C. Barker, Nour Elmestekawy, Elizabeth Goghomu, and Zulfiqar Ahmed Bhutta

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Women's health and well-being in five birth cohorts from low- and middle-income countries: Domains and their associations with early-life conditions, Fernando Pires Hartwig, Anushka Ataullahjan, Linda Adair, Helen Gonçalves, Bernardo Horta, Nanette Lee, Reynaldo Martorell, Ana Maria B. Menezes, Janaina Vieira Dos Santos Motta, and Zulfiqar Ahmed Bhutta

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Choosing the right equation for calculating indirect LDL-Cholesterol (LDL-C) in adult Pakistani population: Evaluation of seven equations using big data analytics, Syed Bilal Hashmi, Sibtain Ahmed, Shiraz Hashmi, Rasool Bux, and Imran Siddiqui

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Behavior change interventions to address unhealthy food consumption: A scoping review, Shivani Kachwaha, Sunny S. Kim, Jai K. Das, Sabrina Rasheed, SubbaRao M. Gavaravarapu, Pooja Pandey Rana, and Purnima Menon

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The spectrum of acute illness and mortality of children and adolescents presenting to emergency services in Sanghar district hospital, Pakistan: A prospective cohort study, Fiona Muttalib, Zahid Ali Memon, Shah Muhammad, Asif Soomro, Samia Khan, Shazia Bano, Muhammad Jawwad, Sajid Bashir Soofi, Bettina Hansen, and Zulfiqar Ahmed Bhutta

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Antibiotics for acute watery or persistent with or without bloody diarrhoea in children: A systematic review and meta-analysis, Syeda Kanza Naqvi, Mustafa Bin Ali Zubairi, Ayesha Arshad Ali, Ashraf Sharif, Rehana Abdus Salam, Zain Hasnain, Sajid Bashir Soofi, Shabina Ariff, Yasir Bin Nisar, and Jai K. Das

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Technology-assisted mental health intervention delivered by frontline workers at community doorsteps for reducing anxiety and depression in rural Pakistan: Protocol for the mPareshan mixed methods implementation trial, Fauziah Rabbani, Javeria Nafis, Samina Akhtar, Muhammad Shahid Khan, Saleem Sayani, Amna Siddiqui, Sameen Siddiqi, and Zul Merali

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Neonatal bacterial sepsis, Tobias Strunk, Eleanor J. Molloy, Archita Mishra, and Zulfiqar Ahmed Bhutta

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Optimal strategies for screening common birth defects in children of low- and middle-income countries: A systematic review, Umaima Zaki, Saqib Hamid Qazi, Urooj Shamim, Shibrah Fatima, Jai K. Das, and Zulfiqar Ahmed Bhutta

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Low-osmolarity oral rehydration solution for childhood diarrhoea: A systematic review and meta-analysis, Mustafa Bin Ali Zubairi, Syeda Kanza Naqvi, Ayesha Arshad Ali, Ashraf Sharif, Rehana Abdus Salam, Zain Hasnain, Sajid Bashir Soofi, Shabina Ariff, Yasir Bin Nisar, and Jai K. Das

Submissions from 2023

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Parental acceptance of typhoid conjugate vaccine for children aged 6 months to 15 years in an outbreak setting of Lyari Town Karachi, Pakistan, Rabab Batool, Mohammad Tahir Yousafzai, Sonia Qureshi, Sajid Muhammad, Ibtisam Qazi, Tahira Sadaf, Per Ashorn, and Farah Qamar

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The last mile-community engagement and conditional incentives to accelerate polio eradication in Pakistan: Study protocol for a quasi-experimental trial, Jai K. Das, Amira Khan, Farhana Tabassum, Zahra Ali Padhani, Atif Habib, Mushtaq Mirani, Abdu R. Rahman, Zahid Ali Khan, Arjumand Rizvi, and Imran Ahmed

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Exploring knowledge and perceptions of polio disease and its immunization in polio high-risk areas of Pakistan, Atif Habib, Farhana Tabassum, Imtiaz Hussain, Tooba Jawed Khan, Nazia Syed, Fariha Shaheen, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Optimal timing of introduction of complementary feeding: A systematic review and meta-analysis, Zahra A. Padhani, Jai K. Das, Faareha A. Siddiqui, Rehana A. Salam, zohra S. lassi, Durray Shahwar Abid Khan, Ammaar M A Abbasi, Emily C. Keats, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia, Zahra Ali Padhani, Manesh Kumar Gangwani, Alina Sadaf, Babar Hasan, Steven Colan, Najveen Alvi, and Jai K. Das

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COHESION: A core outcome set for the treatment of neonatal encephalopathy, Fiona A. Quirke, Shabina Ariff, Malcolm R. Battin, Caitlin Bernard, Linda Biesty, Frank H. Bloomfield, Mandy Daly, Elaine Finucane, Maira Niaz, and Farhana Tabassum

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Multi-round versus Real-Time Delphi survey approach for achieving consensus in the COHESION core outcome set: A randomised trial, Fiona A. Quirke, Malcolm R. Battin, Caitlin Bernard, Linda Biesty, Frank H. Bloomfield, Mandy Daly, Elaine Finucane, David M. Haas, Maira Niaz, and Farhana Tabassum

Submissions from 2022

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Characteristics and birth outcomes of pregnant adolescents compared to older women: An analysis of individual level data from 140,000 mothers from 20 RCTs, Nadia Akseer, Emily Catherine Keats, Pravheen Thurairajah, Simon Cousens, Ana Pilar Bétran, Brietta M. Oaks, David Osrin, Ellen Piwoz, Exnevia Gomo, and Zulfiqar Ahmed Bhutta

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Perpetuation of gender discrimination in Pakistani society: Results from a scoping review and qualitative study conducted in three provinces of Pakistan, Tazeen Saeed Ali, Shahnaz Shahid Ali, Sanober Nadeem, Zahid Memon, Sajid Bashir Soofi, Falak Madhani, Yasmin Karim, Shah Mohammad, and Zulfiqar Ahmed Bhutta

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Risk factors for community-acquired bacterial infection among young infants in South Asia: A longitudinal cohort study with nested case–control analysis, Nicholas E. Connor, Mohammad Shahidul Islam, Luke C. Mullany, Nong Shang, Zulfiqar Ahmed Bhutta, Anita K. M. Zaidi, Sajid Bashir Soofi, Muhammad Imran Nisar, Pinaki Panigrahi, and Kalpana Panigrahi

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Alleviating hidden hunger: An infallible bridge to improved health and nutrition, Jai K. Das and Zahra Ali Padhani

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Mental health and positive development prevention interventions: Overview of systematic reviews, Leila Harrison, Naeha Sharma, Omar Irfan, Michele Zaman, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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Improving health and social systems for all children in LMICs: Structural innovations to deliver high-quality services, Margaret E. Kruk, Todd P. Lewis, Catherine Arsenault, Zulfiqar Ahmed Bhutta, Grace Irimu, Joshua Jeong, Zohra S. Lassi, Susan M. Sawyer, Tyler Vaivada, and Peter Waiswa

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Building knowledge, optimising physical and mental health and setting up healthier life trajectories in South African women ( Bukhali): A preconception randomised control trial part of the Healthy Life Trajectories Initiative (HeLTI), Shane A. Norris, Catherine E. Draper, Alessandra Prioreschi, C M Smuts, Lisa Jayne Ware, CindyLee Dennis, Philip Awadalla, D Bassani, Zulfiqar Ahmed Bhutta, and Laurent Briollais

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Tackling Protein-Calorie Malnutrition during world crises, Zahra Ali Padhani, Jai K. Das, Saeed Akhtar, Tariq Ismail, and Zulfiqar Ahmed Bhutta

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Delivery strategies supporting school-age child health: A systematic review, Naeha Sharma, Ayesha Asaf, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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What can work and how? An overview of evidence-based interventions and delivery strategies to support health and human development from before conception to 20 years, Tyler Vaivada, zohra S. lassi, Omar Irfan, Rehana Salam, Jai K. Das, Christina Oh, Bianca Carducci, Reena P. Jain, Daina Als, and Zulfiqar Ahmed Bhutta

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Effects of early-life poverty on health and human capital in children and adolescents: Analyses of national surveys and birth cohort studies in LMICs, Cesar G. Victora, Fernando P. Hartwig, Luis P. Vidaletti, Reynaldo Martorell, Clive Osmond, Linda M. Richter, Aryeh D. Stein, Aluisio J D. Barros, Linda S. Adair, and Zulfiqar Ahmed Bhutta

Submissions from 2021

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Conflict, extremism, resilience and peace in south Asia; can covid-19 provide a bridge for peace and rapprochement?, Zulfiqar Ahmed Bhutta, Arun Mitra, Afsah Salman, Fawad Akbari, Suraya Dalil, Fyezah Jehan, Mushtaque Chowdhury, Saroj Jayasinghe, Purnima Menon, and Samiran Nundy

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A century past the discovery of insulin: Global progress and challenges for type 1 diabetes among children and adolescents in low-income and middle-income countries, Zulfiqar Ahmed Bhutta, Rehana A. Salam, Apoorva Gomber, Laura Lewis-Watts, Tanya Narang, Jean Claude Mbanya, and George Alleyne

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Addressing production gaps for vaccines in African countries, Anna Mia Ekström, Göran Tomson, Rhoda K. Wanyenze, Zulfiqar Ahmed Bhutta, Catherine Kyobutungi, Agnes Binagwaho, and Ole Petter Ottersen

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World Health Organization and knowledge translation in maternal, newborn, child and adolescent health and nutrition, STAGE (Strategic Technical Advisory Group of Experts), Trevor Duke, Fadia S. AlBuhairan, Koki Agarwal, Narendra K. Arora, Sabaratnam Arulkumaran, Zulfiqar Ahmed Bhutta, Fred Binka, Arachu Castro, and Fyezah Jehan

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Combined clinical audits and low-dose, high-frequency, in-service training of health care providers and community health workers to improve maternal and newborn health in Mali: Protocol for a pragmatic cluster randomized trial, David Zombre, Jean-Luc Kortenaar, Farhana Zareef, Moussa Doumbia, Sekou Doumbia, Fadima Haidara, Katie McLaughlin, Samba Sow, Zulfiqar Ahmed Bhutta, and Diego G. Bassani