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MPhil in Biological and Biomedical Sciences

Theses/Dissertations from 2024 2024

Exploring the role of Wnt, Nfκb, and pi3 kinase pathways in oxaliplatin-resistant triple-negative breast carcinoma cell line, Asif Ahmed

Fixing B-thalassemia causing genetic variants by the aid of prime editing tools, Susheel Fatima

Cord blood-derived hematopoietic stem cell differentiation into erythroid cells, Samreen Feroz

Contribution of kras/ral pathway in growth and progression of colorectal cancer, Nazia Jan

Integrating exome sequencing, gene editing, and cellular reprogramming for diagnosis and therapeutic advancements in mendelian disorders, Hareem Nizam

Identification of single nucleotide polymorphism of anti mullerian hormone (AMH) polycystic ovary syndrome, Laiba Rehmat

A proof-of-concept study on depression frequency, genetic polymorphisms, and bioinformatics in metabolic syndrome compared to healthy individuals, Nida Sadiq

Next generation sequencing of host mitochondrial DNA to elucidate host response in COVID-19 crisis, Shazveen Saleem

Genetic variation in VDR alters immune response in COVID-19, Mishal Shaheen

Effect of carum copticum benth and thymol on biochemical and behavioural alterations in alzheimer's disease, Ayesha Siddiqua

Age and sex related expression of RHO associated protein rock 1 & 2 in myocardial infarction, Hareem Siddiqui

Beneficial role of moringa oleifera in modulating behavioral and neuronal outcomes in a rat model of temporal lobe epilepsy with hippocampal sclerosis, Sofia Yaqoob

Theses/Dissertations from 2023 2023

Role of oxidative stress in cancer cell death induced by natural/synthetic agents, Yousuf Tahir Ali

Molecular insights into infertile polycystic ovary syndrome by using mass spectrometry based proteomics, Sabeen Fatima

Pharmacological basis for cardio-protective effects of aniseed and caraway, alone and in combination, using ex-vivo and in-vivo animal models, Zabrain Gul

Role of carum carvi in reducing depression and improving memory loss in temporal lobe epilepsy with hippocampal sclerosi., Syeda Arfa Mairaj

Role of prostacyclin analogue in curbing thrombotic complications of type 2 diabetes mellitus, Syeda Pinar Nasir

Investigating expression of activating receptor ligands of natural killer cells in acute myeloid leukemia, Nishat Pervez

Age and sex specific responses of myocardial infarction, Kiran Rashid

Investigating drug repurposing: Digoxin-induced cell death alone or combined with hyperthermia in human monocytic leukemia U937 cells., Yasmeen Rind

The hunger genes: Effect of methylation of genes regulating satiety in metabolicallyhealthy and unhealthy individuals, Fizza Salman

JAK/STAT and TGF-β pathway signaling in epithelial-tomesenchymal transition (EMT) of ebv-associated prostate cancer cell line, Asif Ali Shah

Combining genomics and functional studies to understand rare neurological disorders, Hijab Zahra

Theses/Dissertations from 2022 2022

Identification of Alzheimer’s disease related highly susceptible gene mutation in Pakistani population: A pilot study, Rabia Aiman

Association of microRNAs (miR-21, miR-374 and miR-126) with autophagy in malignant glioma, Wajiha Amin

Identification and functional analysis of variants associated with rare mendelian disorders in Pakistani population, Sohana Nadeem Hashmi

Targeting PI3K/AKT/MTOR pathway and anti-apoptotic protein xiap in chemotherapy-resistant colorectal cancer cells, Rozmeen Badruddin Husein

Animal modelling of alzheimer’s disease and novel drug intervention to prevent memory loss, Shabina Jabeen

Elucidating the genetic bases of selected rare disorders in consanguineous families, Lubaba Bintee Khalid

Detection and characterization of salmonella typhi and S. paratyphi A from sewage samples, Wardah Mujahid

Zingiber officinale improves seizures, depression, memory and hippocampal sclerosis in temporal lobe epilepsy., Mehr Murad Musani

Role of aldehyde dehydrogenase 1 (ALDH1) and transmembrane and immunoglobulin-containing domain 1 (TMIGD1) in colorectal cancer, Shehla Rabia

Genomic characterization of environmental and clinical vibrio cholerae strains, Javeria Samad

Identification of risk alleles in infertile females with polycystic ovary syndrome: Validation of genome wide association studies (GWAS) in Pakistani population, Zainab Hanif Samma

WNT inhibition and apoptosis in mice myocardial infarction and ischemia reperfusion injury models., Rena Zaman

Theses/Dissertations from 2021 2021

Use of saffron and chamomile in the treatment of depression in rats, and investigation of their mechanism of action using bioinformatics., Faiq Amin

Analysis of host-specific miRNAs in EBV-associated prostate cancers., Ali Salman Sheikh

Role of NRF2 and WNT pathway in regulating oxidative stress after myocardial ischemia reperfusion injury, Sahar Khalid Zuberi