Three unusual primary tumours of the adrenal gland
Document Type
Article
Department
Pathology (East Africa)
Abstract
Three unusual primary tumours of the adrenal gland are highlighted. Awareness of these unusual entities will prevent misdiagnosis and allow proper work-up to achieve the correct diagnosis. The first case is an adrenal angiomyolipma which is usually sporadic but can occur in tuberous sclerosis as well. Often times this can be mistaken for a smooth muscle tumour or an angio/myelolipoma or even a lipoma. Search for all three components will achieve the correct diagnosis together with confirmatory immunohistochemistry. Primary adrenal solitary fibrous tumour can masquerade as other spindle cell fibrous appearing tumours. Search for the haemangiopericytic vasculature or even amianthoid-like foci are useful. Staining for STAT-6 is diagnostic. Lastly, combined phaeochromocytoma-ganglioneuroma can be missed with inadequate sampling and not paying attention for the background Schwannian component, and the presence of ganglion cells.
Publication (Name of Journal)
Diagnostic Histopathology
DOI
https://doi.org/10.1016/j.mpdhp.2026.08.001
Recommended Citation
Mwandoto, I.,
Noordin, W.,
Chetty, R.
(2026). Three unusual primary tumours of the adrenal gland. Diagnostic Histopathology, 1-5.
Available at:
https://ecommons.aku.edu/eastafrica_fhs_mc_pathol/336