Burden and risk of neurological and cognitive impairment in pediatric sickle cell anemia in Uganda (BRAIN SAFE): Interim 0verall results.

Document Type

Article

Department

Paediatrics and Child Health (East Africa)

Abstract

Sickle Cell Anemia (SCA) is highly prevalent in sub-Saharan Africa (SSA). In Uganda, approximately 20,000 children are born with SCA annually (Ndeezi G, 2016). Sickle brain vasculopathy causes both overt strokes and clinically "silent infarcts," affecting neurological and cognitive function (DeBaun MR, 2012). Incidence of strokes has markedly decreased through standardized preventative measures. Study objectives are to determine the age-related spectrum and burden of brain injury associated with SCA in Ugandan children, determine predisposing risk factors and build capacity to support interventions for stroke prevention. Here we present preliminary results.

Comments

This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Blood

DOI

https://doi.org/10.1182/blood.V130.Suppl_1.979.979

Share

COinS