Reaching beyond pregnant women to eliminate mother-to-child transmission of syphilis in Africa
Obstetrics and Gynaecology (East Africa); Centre of Excellence in Women and Child Health
Congenital syphilis is a devastating disease that can be prevented by screening and treatment of infected pregnant women. The WHO is leading a global initiative to eliminate mother-to-child-transmission of syphilis with a goal of ≤50 congenital syphilis cases per 100,000 live births and targets of 95% antenatal care, 95% syphilis testing, and 95% treatment coverage. We estimated current congenital syphilis rates for 43 African countries, and additional scenarios in a subset of 9 countries. Our analysis suggested that only 4 of 43 countries are likely to currently have a congenital syphilis rate ≤50 per 100,000 live births, and none of the 9 countries could reach this goal even in 5 different scenarios with improved services. To achieve the eliminate mother-to-child-transmission goal, it appears necessary to intervene beyond services for pregnant women, and decrease prevalence of syphilis in the general population as well.
Publication ( Name of Journal)
Expert Review of Anti-infective Therapy
Trope, L. A.,
Wijesooriya, N. S.,
(2014). Reaching beyond pregnant women to eliminate mother-to-child transmission of syphilis in Africa. Expert Review of Anti-infective Therapy, 12(6), 705-714.
Available at: https://ecommons.aku.edu/eastafrica_fhs_mc_obstet_gynaecol/503