Transvenous pacing causing tamponade in patients receiving glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention

Document Type



Internal Medicine (East Africa)


A backup temporary pacing wire is often used in patients with heart block undergoing cardiac catheterization and percutaneous coronary intervention (PCI). It is particularly recommended for any patient undergoing rotational atherectomy or rheolytic thrombectomy when the vessel involved is the right coronary artery (RCA) or a dominant left circumflex artery (LCx).1,2

In recent years, there has been a marked increase in the use of glycoprotein IIb/IIIa inhibitors in patients with acute coronary syndromes prior to planned coronary intervention and also in patients undergoing elective but complex coronary intervention in line with evidence-based practice. We present four cases in which cardiac tamponade occurred following temporary pacing in patients who had received glycoprotein IIb/IIIa inhibitors during invasive cardiac procedures.


This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Journal of Invasive Cardiology