Submissions from 2024
Neutralizing immunity against coronaviruses in Tanzanian health care workers, Godfrey Barabona, Isaac Ngare, Doreen Kamori, Lilian Nkinda, Yusuke Kosugi, Yusuke Kosugi, Ambele Mawazo, Rayi Ekwabi, Gloria Kinasa, and Harrison Chuwa
Early goal-directed hemostatic therapy for severe acute bleeding management in the intensive care unit: a narrative review., Tomaz Crochemore, Klaus Görlinger, and Marcus Lance
Epidemiology, clinical characteristics, and Outcomes of 4546 Adult Admissions to High-Dependency and ICUs in Kenya: A multicenter registry-based observational study., Carolyne Njoki; Simiyu, Nabukwangwa; Kaddu Ronnie; Sulemanji Demet; Oduor Peter; Dona Dilanthi Gamage; Otieno Dorothy; Abonyo Teddy Thaddeus; Mutuku Selina; Muthoni Joy; David Misango; and Wangari Siika
Editorial: Critical care applications: bridging high, medium and low-income settings., Luigi Pisani, Wangari Siika, and Madiha Hashmi
Submissions from 2023
Surgical research—comic opera no more, Jessamy Bagenal, Naomi Lee, Adesoji O. Ademuyiwa, Dmitri Nepogodiev, Antonio Ramos-De la Medina, Bruce Biccard, Marie Carmela Lapitan, and Wangari Siika
Early goal-directed hemostatic therapy for severe acute bleeding management in the Intensive Care Unit: A narrative review, Tomaz Crochemore, Görlinger Klaus, and Marcus Lance
Management and outcomes of pregnant ICU patients with severe COVID-19 pneumonia in Qatar: A retrospective cohort study, Hayat Elfil, Mogahed Ismail Hassan Hussein, Layla J. M. Kily, Sohel M. G. Ahmed, Mohammed Janish, Salwa M. Abuyaqoub, Huda A. Saleh, and Marcus Lance
Inferior vena cava collapsibility index versus passive leg raise to assess fluid responsiveness in non-intubated septic patients a prospective observational study, Anne Githaiga, Wangari Siika, Jeilan Mohamed, Vitalis Mung’ayi, and Idris Chikophe
Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care, Sibylle Kietaibl, Aamer Ahmed, Arash Afshari, Pierre Albaladejo, Cesar Aldecoa, Giedrius Barauskas, Edoardo De Robertis, David Faraoni, Daniela Filipescu, and Marcus Lance
Sensitivity of a preanaesthesia screening and triage tool in identifying high-risk patients attending the preanaesthesia assessment clinic in a tertiary referral hospital in Sub-Saharan Africa: a diagnostic accuracy study, Brian Misoi, Vitalis Mung’ayi, Rajpreet Bal, and Shamshudin Mohammedali
Evaluation of hydrocortisone, vitamin c, and thiamine for the treatment of septic shock: a randomized controlled trial (the HYVITS trial), Adham Mohamed, Mohamed Abdelaty, Mohamed O. Saad, Ahmed Shible, Hassan Mitwally, Abdel-Rauof Akkari, Abdurrahmaan Elbuzidi, Awadh Bintaher, Ahmed Hashim, and Marcus Lance
Organisation, staffing and resources of critical care units in Kenya, Wambui Mwangi, Ronnie Kaddu, Carolyne Njoki Muiru, Nabukwangwa Simiyu, Vishal Patel, Demet Sulemanji, Dorothy Otieno, David Misango, Wangari Siika, and Rashan Haniffa
Red blood cell transfusion in the intensive care unit, Senta Jorinde Raasveld, Sanne de Bruin, Merijn C. Reuland, Claudia van den Oord, Jimmy Schenk, Cécile Aubron, Jan Bakker, Maurizio Cecconi, Aarne Feldheiser, and Marcus Lance
WHO O2CoV2: oxygen requirements and respiratory support in patients with COVID-19 in low-and-middle income countries—protocol for a multicountry, prospective, observational cohort study, Pryanka Relan, Srinivas Murthy, John Marshall, Djillali Annane, Sylvie Chevret, Yaseen Arabi, Wangari Siika, Sara Dominguez Rodriguez, Pauline Convocar, and Janet Diaz
A health systems approach to critical care delivery in low-resource settings: a narrative review, Stephen A. Spencer, Faustina Excel Adipa, Tim Baker, Ana Maria Crawford, Paul Dark, Dingase Dula, Stephen B. Gordon, David Oliver Hamilton, Dawit Kebede Huluka, and Wangari Siika
Submissions from 2022
The State of Critical Care Provision in Low-Resource Environments, Bruce Biccard, Tim Baker, Delia Mabedi, and Wangari Siika
Worldwide clinical intensive care registries response to the pandemic: An international survey, Dave A. Dongelmans, Amanda Quintairos, Eirik Alnes Buanes, Diptesh Aryal, Sean Bagshaw, Stepani Bendel, Joe Bonney, Gaston Burghi, Eddy Fan, and Wangari Siika
A systematic review of substance use and substance use disorder research in Kenya, Florence Jaguga, Sarah Kanana Kiburi, Eunice Temet, Julius Barasa, Serah Karanja, Lizz Kinyua, and Edith Kamaru Kwobah
Conversion of dissertations to publications at the Aga Khan University Kenya: an exploratory study of residents perceptions and experiences, Brigette Macharia
Current State of Critical Care Nursing Worldwide, Eunice Ndirangu, Lia M. Barros, Bernard Mutwiri, Constance Shumba, Beth Waweru, and Wangari Siika
Theses/Dissertations from 2021
Effectiveness of Pain Control of Local Anaesthetic Wound Infusion Following Elective Midline Laparotomy: A Randomized Trial, David Gathege, Abdallah Abdulkarim, David Odaba, and Stanley Mugambi
Inferior vena cava collapsibility index versus passive leg raise for the assessment of fluid responsiveness in non-intubated spontaneously breathing septic patients, Anne-Marie Githaiga
The Effect of Saline Flush After Rocuronium Bolus on Intubating Conditions in Adult Patients Undergoing Elective Surgery: A Randomized Controlled Trial, Ian Odari, Vitalis Mung’ayi, Rajpreet Bal, and David Odaba
Determinants of preconception care among pregnant women in an urban and a rural health facility in Kenya: a qualitative study, Joan Okemo, Dorothy Kamya, Mukaindo Mwaniki, and Marleen Temmerman
Critically ill COVID-19 patients in Africa: it is time for quality registry data, Luigi Pisani, Wangari Siika, Cornelius Sendagire, Abi Beane, and Rashan Haniffa
Self-reported knowledge, attitudes, practices and barriers in use of evidence-based medicine among resident physicians in Kenya: a mixed methods study, Megha Unadkat, Caroline K. Mbuba, Anthony Ngugi, and Dorothy Kamya
Theses/Dissertations from 2020
Investigating SOFA, delta-SOFA and MPM-III for mortality prediction among critically ill patients at a private tertiary hospital ICU in Kenya: A retrospective cohort study, Lillian N. Lukoko, Peter S. Kussin, Rodney Adam, James Orwa, and Wangari Siika
Preconception Care among Pregnant Women in an Urban and a Rural Health Facility in Kenya: A Quantitative Study, Joan Okemo, Marleen Temmerman, Mukaindo Mwaniki, and Dorothy Kamya
Knowledge and Perceptions Regarding Palliative Care Among Religious Leaders in Uasin Gishu County, Kenya: Survey and Focus Group Analysis, Faith Rialem, Jessie P. Gu, Violet Naanyu, Zipporah Ali, Patrick Chege, Dinah Chelagat, Millicent Korir, Wangari Siika, and Peter S. Kussin
Building focused cardiac ultrasound capacity in a lower middle-income country: A single centre study to assess training impact, Wangari Siika, Anders Barasa, Benjamin Wachira, David Nekyon, Barbara Karau, Fatimah Juma, Grace Wanjiku, Harun Otieno, Gerald S. Bloomfield, and Erik Sloth
Submissions from 2019
Sepsis Management in a Resource-Limited Setting: A Clinical Trial of Quantitative Resuscitation in a National Referral Hospital in Kenya, L. Boole, Wangari Siika, C. Kwobah, G. S. Bloomfield, N. Thielman, and P. S. Kussin
Effect of video-based information on pre-operative state trait anxiety inventory scores in adult patients presenting for elective caesarean section, Timothy Kanyeki
Chronic post mastectomy pain in adult female patients at Aga Khan University Hospital Nairobi, Jared Owour Mbete
Effect of target controlled propofol infusion versus intermittent boluses during oesophagogastroduodenoscopy: a randomized controlled trial, Catherine Ndosi, Vitalis Mung’ayi, Ednah Gisore, and Samina Mir
Effect of removal of AuraOnce™ laryngeal mask in awake or deep anaesthesia: a randomized controlled trial, Ronald Ombaka, Vitalis Mung’ayi, David Nekyon, and Samina Mir
Effect of low-dose ketamine versus fentanyl on attenuating the haemodynamic response to laryngoscopy and endotracheal intubation in patients undergoing general anaesthesia: a prospective, double-blinded, randomised controlled trial, Angela Ongewe, Vitalis Mung’ayi, and Rajpreet Bal
The effect of premedication with Intravenous Lornoxicam on Propofol injection pain at induction of general Anaesthesia in adults: a randomised placebo-controlled trial, Dennis Omari Onyancha
The history of critical care in Kenya, Wangari Siika, Vitalis Mung’ayi, David Misango, Andrea Mogi, Alan Kisia, and Zipporah Ngumi
A randomised controlled trial of the effect of laryngeal mask airway manometry on postoperative sore throat in spontaneously breathing adult patients presenting for surgery at a university teaching hospital, David Waruingi, Vitalis Mung’ayi, Ednah Gisore, and Sikolia Wanyonyi
Submissions from 2018
A randomized control trial comparing train of four ratio > 0.9 to clinical assessment of return of neuromuscular function before endotracheal extubation on critical respiratory events in adult patients undergoing elective surgery at a tertiary hospital in Nairobi, Isaac Adembesa, Vitalis Mung’ayi, Zul Premji, and Dorothy Kamya
Haemodynamic assessment and support in sepsis and septic shock in resource-limited settings, David Misango; Rajyabardhan Pattnaik; Tim Baker; Martin W. Dünser; Arjen M. Dondorp; Marcus J. Schultz; and Global Intensive Care Working Group†, of the European Society of Intensive Care Medicine (ESICM) and the Mahidol Oxford Tropical Medicine Research Unit (MORU) in Bangkok, Thailand
A comparison of risk of hypotension using standard doses of remifentanil versus dexmedetomidine infusions in adult patients undergoing surgery under general anaesthesia at the Aga Khan University Hospital, Nairobi, Maxine Onyango Okello, Vitalis Mung’ayi, Rodney Adam, and Jimmie Kabugi
Submissions from 2017
The effect of a preanaesthesia clinic consultation on adult patient anxiety at a tertiary hospital in Kenya: a cohort study, Anthony Kamau, Vitalis Mung’ayi, and Gerald Yonga
Worldwide Survey of the "Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment" (ABCDEF) Bundle, Alessandro Morandi, Simone Piva, E. Wesley Ely, Sheila Nainan Myatra, Jorge I.F. Salluh, Dawit Amare, Elie Azoulay, Giuseppe Bellelli, Akos Csomos, Eddy Fan, Nazzareno Fagoni, Timothy Girard, Gabriel Heras La Calle, Shigeaki Inoue, Chae-Man Lim, Rafael Kaps, Katarzyna Kotfis, Younsuck Koh, David Misango, Pratik P. Pandharipande, Chairat Permpikul, Cheng Cheng Tan, Dong-Xin Wang, Tarek Sharshar, Yahya Shehabi, Yoanna Skrobik, Jeffrey M. Singh, Arjen Slooter, Martin Smith, Ryosuke Tsuruta, and Nicola Latronico
A randomized controlled trial to assess the effect of a ketamine infusion on tourniquet hypertension during general anaesthesia in patients undergoing upper and lower limb surgery, Joyce Atieno Ongaya, Vitalis Mung’ayi, Sharif Thikra, and Jimmie Kabugi
Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future, Marcus J. Schultz, Martin W. Dunser, Arjen M. Dondorp, Neill K. J. Adhikari, Shivakumar Iyer, Arthur Kwizera, Yoel Lubell, Alfred Papali, Luigi Pisani, Beth D. Riviello, Derek C. Angus, Luciano C. Azevedo, Tim Baker, Janet V. Diaz, Emir Festic, Rashan Haniffa, Randeep Jawa, Shevin T. Jacob, Niranjan Kissoon, Rakesh Lodha, Ignacio Martin-Loeches, Ganbold Lundeg, David Misango, Mervyn Mer, Sanjib Mohanty, Srinivas Murthy, Ndidiamaka Musa, Jane Nakibuuka, Ary Serpa Neto, Mai Nguyen Thi Hoang, Binh Nguyen Thien, Rajyabardhan Pattnaik, Jason Phua, Jacobus Preller, Pedro Povoa, Suchitra Ranjit, Daniel Talmor, Jonarthan Thevanayagam, and C. Louise Thwaites
International Surviving Sepsis Campaign guidelines 2016: the perspective from low-income and middle-income countries, Gentle S. Shrestha, Arthur Kwizera, Ganbold Lundeg, John I. Baelani, Luciano C. P. Azevedo, Rajyabardhan Pattnaik, David Misango, and Rashan Haniffa
Submissions from 2016
A randomised controlled trial comparing the effect of adjuvant intrathecal 2 mg midazolam to 20 micrograms fentanyl on postoperative pain for patients undergoing lower limb orthopaedic surgery under spinal anaesthesia, Francis Codero, Vitalis Mung’ayi, and Sharif Thikra
Comparison of Weight Adjusted Dose Versus Fixed Dose Ondansetron in Preventing Shivering following Spinal Anesthesia for Cesarean Deliveries, Moses Kimuri Gicheru
A randomised controlled trial comparing weight adjusted dose versus fixed dose prophylactic phenylephrine infusion on maintaining systolic blood pressure during caesarean section under spinal anaesthesia, Lucy Mwaura, Vitalis Mung’ayi, Jimmie Kabugi, and Samina Mir
Predicting Mortality in Low-Income Country ICUs: The Rwanda Mortality Probability Model (R-MPM), Elisabeth D. Riviello, Willy Kiviri, Robert A. Fowler, Ariel Mueller, Victor Novack, Valerie M. Banner-Goodspeed, Julia L. Weinkauf, Daniel S. Talmor, and Theogene Twagirumugabe
Effect of Laryngeal Mask Airway Manometry on Post-operative Sore Throat in spontaneously breathing Adult Patients presenting for Surgery at Aga Khan University Hospital, Nairobi, David Njoroge Waruingi
Theses/Dissertations from 2015
A randomized controlled trial comparing haemodynamic stability in elderly patients undergoing spinal anaesthesia at L5, S1 versus spinal anaesthesia at L3, 4 at a tertiary African hospital., Vitalis Mung’ayi, Karen Mbaya, Sharif Thikra, and Dorothy Kamya
The operational setup of intensive care units in a low income country in East Africa, U K. Okech
The operational setup of intensive care units in a low income country in East Africa, U. K. Okech, T. Chokwe, and Vitalis Mung’ayi
A report from the first regional pain medicine symposia in East, Central and Southern African region. (ECSA-R)-“The Rhino Model in Pain Education in Africa”, Thikra Sharif and John Bugo
Theses/Dissertations from 2014
The effect of a preanaesthesia clinic consultation on adult patient anxiety in Aga Khan University hospital; a cohort study, Anthony Kamau
Blood transfusion and oxygen extraction ratio in patients admitted to the general intensive care unit: A quasi experimental study, Vitalis Mung’ayi, Thikra Sharrif, and David Odaba
Submissions from 2013
Developing a conceptual and practical framework for outcomes measurement to support a quality improvement project in Rwanda: an observational study, Elisabeth DRiviello, Samuel lFinlayson, Woon ChoKim, Theoneste Mwumvaneza, Willy Kiviri, Sophie Reshamwalla, William Berry, Georges Ntakiyiruta, Patrick Kyamanywa, Edmond Ntaganda, and Theogene Twagirumugabe
The prevalence of postoperative pain in the first 48 hours following day surgery at a tertiary hospital in Nairobi, Gilbert Mwaka, Shariff Thikra, and Vitalis Mung’ayi
Effects of intravenous diclofenac on postoperative sore throat in patients undergoing laparoscopic surgery at Aga Khan University Hospital, Nairobi: a prospective, randomized, double blind controlled trial, Thang'a P., Dorothy Kamya, and Vitalis Mung’ayi
Theses/Dissertations from 2012
Submissions from 2011
Course and outcome of obstetric patients admitted to a University Hospital Intensive Care Unit, F. Githae, Vitalis Mung’ayi, and William Stones
Pain control for uterine fibroid embolisation : An initial experience in East Africa., Gilbert Mwaka, Vitalis Mung’ayi, Nigel Hacking, and William. Stones
Submissions from 2010
Incidence of post dural puncture headache following caesarean section under spinal anaesthesia at the Aga Khan University Hospital, Nairobi, Edna Gisore, Vitalis Mung’ayi, and Sharif T.
Conformity to the surviving sepsis campaign international guidelines among physicians in a general intensive care unit in Nairobi, Vitalis Mung’ayi and R. Karuga
Submissions from 2009
Tetanus in developing countries: a case series and review, Kara Gibson, J Bonaventure Uwineza, Willy Kiviri, and Joel Parlow
Cumulative incidence of post dural puncture headache following caesarean section under spinal anaesthesia at The Aga Khan University Hospital Nairobi, Ednah K. Gisore
Life threatening spinal shock and complete neurological recovery following minor spinal cord trauma in a patient with pre-existing cervical canal stenosis: case report, Vitalis Mung’ayi, Mahmood Qureshi, and John Bugo
The prevalence of postoperative pain following day surgery in the first 48 hours at Aga Khan University Hospital, Nairobi, Gilbert Mwaka
Submissions from 2008
Knowledge, attitude and use of labour pain relief methods among women attending antenatal clinic in Nairobi, Vitalis Mung’ayi, D. Netyton, and Robinson Karuga