Sickle Cell Disease in Pregnancy: Trend and Pregnancy Outcomes at a Tertiary Hospital in Tanzania

Authors

Projestine S. Muganyizi, Muhimbili University of Health and Allied Sciences, Dar es Salaam
Hussein Kidanto, Aga Khan UniversityFollow

Document Type

Article

Department

Obstetrics and Gynaecology (East Africa)

Abstract

SCD in pregnancy is associated with increased adverse fetal and maternal outcomes. In Tanzania where the frequency of sickle cell trait is 13% there has been scanty data on SCD in pregnancy. With progressive improvement in childhood survival the burden of SCD in pregnancy will increase. We analyzed all deliveries at Muhimbili National Hospital (MNH) from 1999 to 2011. Fetal and maternal outcomes of SCD deliveries were compared with non-SCD. Data were analyzed using IBM SPSS statistics version 19. Chi square and Fisher Exact tests were used to compare proportions and the independent t-test for continuous data. To predict risks of adverse effects, odds ratios were determined using multivariate logistic regression. A p-value

Comments

This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

PloS one

Recommended Citation

Muganyizi, P. S., & Kidanto, H. (2013). Sickle cell disease in pregnancy: trend and pregnancy outcomes at a tertiary hospital in Tanzania. PloS one, 8(2), e56541.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.