Ependymal creeping on mri as a differentiating feature of high grade gliomas
Location
Auditorium Pond Side
Start Date
26-2-2014 10:30 AM
Abstract
Gliomas are the most common primary tumors of the brain, early and correct diagnosis of the disease is essential in improving survival. High grade lesions are associated with worse prognosis. Our study assesses ependymal creeping on MRI scans as an indicator of high grade lesions. Methodology: Preoperative MRIs of 94 cases were retrospectively reviewed for ependymal creeping. The glioma group consisted of 69 patients and 25 were in the non glioma group. Data was also analyzed separately for high grade lesions and other lesions. Results: Sensitivity of ependymal creeping for glioma vs non glioma lesions was 82.61% specificity 35.42 % (p value=0.048)c.For high grade lesions sensitivity was 67.39 % and specificity of 64.58 %( p value=0.002) Conclusion: Ependymal creeping is sensitive for identification of glial lesions but specificity is not very high. Ependymal creeping shows greater specificity for high grade glial lesions compared with other lesions and may be suggestive of diagnosis aiding in earlier recognition of such lesions, however histological conformation is needed for final diagnosis.
Keywords: Ependymal creeping, MRI, high grade glioma, identification
Ependymal creeping on mri as a differentiating feature of high grade gliomas
Auditorium Pond Side
Gliomas are the most common primary tumors of the brain, early and correct diagnosis of the disease is essential in improving survival. High grade lesions are associated with worse prognosis. Our study assesses ependymal creeping on MRI scans as an indicator of high grade lesions. Methodology: Preoperative MRIs of 94 cases were retrospectively reviewed for ependymal creeping. The glioma group consisted of 69 patients and 25 were in the non glioma group. Data was also analyzed separately for high grade lesions and other lesions. Results: Sensitivity of ependymal creeping for glioma vs non glioma lesions was 82.61% specificity 35.42 % (p value=0.048)c.For high grade lesions sensitivity was 67.39 % and specificity of 64.58 %( p value=0.002) Conclusion: Ependymal creeping is sensitive for identification of glial lesions but specificity is not very high. Ependymal creeping shows greater specificity for high grade glial lesions compared with other lesions and may be suggestive of diagnosis aiding in earlier recognition of such lesions, however histological conformation is needed for final diagnosis.
Keywords: Ependymal creeping, MRI, high grade glioma, identification