Cough as primary complain in case of Sarcoidosis
Location
Auditorium Pond Side
Start Date
26-2-2014 10:30 AM
Abstract
Introduction: Sarcoidosis is a multisystem granulomatous disorder of unknown etiology that affects individuals worldwide and is characterized pathologically by the presence of noncaseating granulomas in involved organs. It typically affects young adults, and initially presents with Bilateral hilar adenopathy, Pulmonary reticular opacities or Skin, joint, and/or eye lesions abnormalities
Case History: Young female with history of cough for 2 month with progressive dyspnea. Clinical examination was unremarkable except she was a bit tachypnic, CT scan done was consistant with nodularities bilateral more distributed along the bronchovascular bundlel ,there was also some ground glass opacities as well.
Bronchoscopy was done which shows bilateral inflamed mucosa with nodularities,BAL was done from right and left upper lobe.,and biopsy was taken from right upper lobe where nodular mucosa was prominent. BAL D/R was consistant with neutrophilic fluid, and biopsy done showsw chronic granulomatous inflammation likely TB or Sarcoid. Her ACE level was also high so with clinical correlation she was labeled as Sarcoid and was started on steroid. All her BAL cultures were negative.
Conclusion: Tuberculosis And Sarcoidosis are very difficult to differentiate even on biopsy , clinical scenario are also very similar so it happens many times that people with Sarcoid got treated with ATT in this part of the globe, so it is necessary to correlate History, clinical examination,and laboratory findigs.
Cough as primary complain in case of Sarcoidosis
Auditorium Pond Side
Introduction: Sarcoidosis is a multisystem granulomatous disorder of unknown etiology that affects individuals worldwide and is characterized pathologically by the presence of noncaseating granulomas in involved organs. It typically affects young adults, and initially presents with Bilateral hilar adenopathy, Pulmonary reticular opacities or Skin, joint, and/or eye lesions abnormalities
Case History: Young female with history of cough for 2 month with progressive dyspnea. Clinical examination was unremarkable except she was a bit tachypnic, CT scan done was consistant with nodularities bilateral more distributed along the bronchovascular bundlel ,there was also some ground glass opacities as well.
Bronchoscopy was done which shows bilateral inflamed mucosa with nodularities,BAL was done from right and left upper lobe.,and biopsy was taken from right upper lobe where nodular mucosa was prominent. BAL D/R was consistant with neutrophilic fluid, and biopsy done showsw chronic granulomatous inflammation likely TB or Sarcoid. Her ACE level was also high so with clinical correlation she was labeled as Sarcoid and was started on steroid. All her BAL cultures were negative.
Conclusion: Tuberculosis And Sarcoidosis are very difficult to differentiate even on biopsy , clinical scenario are also very similar so it happens many times that people with Sarcoid got treated with ATT in this part of the globe, so it is necessary to correlate History, clinical examination,and laboratory findigs.