Paediatrics and Child Health
Objective: To determine the frequency of hyperglycemia in critically ill children admitted in PICU of a tertiary care hospital of Karachi and to compare the mortality of critically ill children with and without hyperglycemia.
Study Design: Cross-sectional study.
Place and Duration of Study: Paediatrics Intensive Care Unit (PICU) of National Institute of Child Health (NICH), Karachi, from November 2011 to April 2012.
Methodology: One hundred fifty critically ill children admitted to PICU were included. Patients who had fasting blood sugar levels more than 126 mg/dl within 48 hours of admission were included in the hyperglycemic group. The normoglycemic and hyperglycemic groups were followed till 10 days to determine the mortality associated with hyperglycemia.
Results: Out of 150 patients, 82 (54.7%) had hyperglycemia. Mortality rate was 48.7% (n=73/150). However, mortality rate was significantly high 57.3% (n=47) in hyperglycemic patients than non-hyperglycemic patients (p=0.019).
Conclusion: The presence of stress-induced hyperglycemia in critically ill patients is a well established marker of poor outcome, and a very high mortality rate. Normoglycemia was associated with favorable outcomes in terms of hospital stay and mortality.
JCPSP: Journal of the College of Physicians and Surgeons Pakistan
Khan, S. A.,
Ibrahim, M. N.,
(2015). Frequency and mortality associated with hyperglycemia in critically Ill children. JCPSP: Journal of the College of Physicians and Surgeons Pakistan, 25(12), 878-881.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_women_childhealth_paediatr/200