The hyper-IgE syndrome with recurrent infections is a rare immunodeficiency disorder characterized by very high levels of IgE in serum. It is inherited in most of the cases in a dominant fashion meaning that it can run in families with a high frequency. About 250 cases have been published in literature so far.
JPMA. The Journal of the Pakistan Medical Association
Samdani, A. J.,
(2004). Cutaneous manifestations of hyper-IgE syndrome in twins: a case report from Saudi Arabia.. JPMA. The Journal of the Pakistan Medical Association, 54(8), 438-439.
Available at: http://ecommons.aku.edu/pakistan_fhs_mc_med_med/432
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