The role of ezetimibe in the treatment of cardiovascular disease
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. Despite the success of treatment of CVD with statin therapy, a number of patients remain at high risk for CVD. Ezetimibe is a non-statin agent that inhibits intestinal cholesterol absorption, leading to reductions in low-density lipoprotein cholesterol (LDL-C). A number of clinical studies evaluating the use of ezetimibe therapy have resulted in discordant data regarding its safety and efficacy. In this review, we discuss the findings from these studies as well as potential indications for the use of ezetimibe for LDL-C lowering and cardiovascular event reduction.
Current Atherosclerosis Reports
Miedema, M. D.,
Virani, S. S.
(2016). The role of ezetimibe in the treatment of cardiovascular disease. Current Atherosclerosis Reports, 18(2), 8.
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Pagination are not provided by the author/publisher. This work was published before the author joined Aga Khan University.