Role of lipid-lowering therapy in peripheral artery disease
Office of the Provost; Cardiology
Atherosclerosis is a multifactorial, lipoprotein-driven condition that leads to plaque formation within the arterial tree, leading to subsequent arterial stenosis and thrombosis that accounts for a large burden of cardiovascular morbidity and mortality globally. Atherosclerosis of the lower extremities is called peripheral artery disease and is a major cause of loss in mobility, amputation, and critical limb ischemia. Peripheral artery disease is a common condition with a gamut of clinical manifestations that affects an estimated 10 million people in the United States of America and 200 million people worldwide. The role of apolipoprotein B-containing lipoproteins, such as LDL and remnant lipoproteins in the development and progression of atherosclerosis, is well-established. The focus of this paper is to review existing data on lipid-lowering therapies in lower extremity atherosclerotic peripheral artery disease.
Journal of clinical medicine
Belur, A. D.,
Shah, A. J.,
Virani, S. S.,
Kalra, D. K.
(2022). Role of lipid-lowering therapy in peripheral artery disease. Journal of clinical medicine, 11(4872).
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Pagination are not provided by the author/publisher. This work was published before the author joined Aga Khan University.