Title
Role of lipid-lowering therapy in peripheral artery disease
Document Type
Review Article
Department
Office of the Provost; Cardiology
Abstract
Atherosclerosis is a multifactorial, lipoprotein-driven condition that leads to plaque formation within the arterial tree, leading to subsequent arterial stenosis and thrombosis that accounts for a large burden of cardiovascular morbidity and mortality globally. Atherosclerosis of the lower extremities is called peripheral artery disease and is a major cause of loss in mobility, amputation, and critical limb ischemia. Peripheral artery disease is a common condition with a gamut of clinical manifestations that affects an estimated 10 million people in the United States of America and 200 million people worldwide. The role of apolipoprotein B-containing lipoproteins, such as LDL and remnant lipoproteins in the development and progression of atherosclerosis, is well-established. The focus of this paper is to review existing data on lipid-lowering therapies in lower extremity atherosclerotic peripheral artery disease.
Publication
Journal of clinical medicine
Recommended Citation
Belur, A. D.,
Shah, A. J.,
Virani, S. S.,
Vorla, M.,
Kalra, D. K.
(2022). Role of lipid-lowering therapy in peripheral artery disease. Journal of clinical medicine, 11(4872).
Available at:
https://ecommons.aku.edu/provost_office/111
Comments
Pagination are not provided by the author/publisher. This work was published before the author joined Aga Khan University.