Document Type

Original Article


Depression is well known common co-morbid psychiatric condition associated with primary epilepsy. This study showed that frequency of depression was 62% in primary epilepsy patient presenting to the Neurology outpatient clinic of a tertiary care hospital. Female gender, high seizures frequency, polytherapy with AEDs and long duration of primary epilepsy were found to be the factors leading to frequent occurrence of depression in primary epilepsy patients Objective: To determine the frequency of depression in patients with primary epilepsy presenting to the Neurology outpatient clinic of Aga Khan University Hospital Karachi.Study Design: Cross-sectional study. Study Setting: Neurology outpatient department at Aga Khan University Hospital, Karachi. Duration of study: 02.11.2009 to 25.08.2010 Patients and Methods: A total of one hundred cases of primary epilepsy patients were enrolled in the study, after informed consent. They were asked to complete the Beck depression inventory while waiting in the neurology outpatient clinic. Patients score more than 9 were diagnosed as depression. Results were analyzed on SPSS version 17.Results: Out of hundred patients 46 (46%) and 54(54%) were male and females respectively. The mean age of the patients was 32.1±14.03. The frequency of depression was found to be (62 %) in primary epilepsy patient. Conclusions: The frequency of depression was found to be very high.

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