Document Type

Review Article


ECerebral venous thrombosis (CVT) is a rare form of venous thromboembolism (VTE). CVT represents almost 0.5% -3% of all the types of stroke, affecting predominantly younger people, with an estimated incidence for adults of 3-4 per million, and for children 7 per million. In the pre-antibiotics era, the leading cause of CVT were septic processes, currently, the aseptic form of CVT predominates. (1) About 75% of all adult patients are women, over the past decade, advances in neuroimaging and treatments have significantly improved the disease’s prognosis with 80% of sufferers having a good neurological outcome. (2) The largest source of international data on the condition, the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT), included 624 patients and reported that 50% of these cases were related to Oral contraceptive pills (OCP), 6% were due to pregnancy and 14% were secondary to puerperium and while looking at the different outcomes found that 356 patients (57.1%) had no symptom or signs, 137 (22%) had minor residual symptoms, and 47 (7.5%) had mild impairments, Eighteen (2.9%) were moderately impaired, 14 (2.2%) were severely handicapped, and 52 (8.3%) had died at the end of follow up (median 16 months)(3). While there is a plethora of research available over the different aspects of CVT internationally, there is a relative paucity of information when focusing on Asia.

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