Rasmussen's encephalitis is a rare baffling disorder seen in nearly 1 % to 2 % of epilepsy population and in 7.4% of paediatric population. It is mostly seen in children and in most cases seizures are seen during 14 months to 14 years with peak age 3 to 6 years. Etiology includes viral infections, humoral autoimmunity and T-cell mediated cyto-toxicity of the brain tissue. The main clinical features are intractable epilepsy, hemiparesis, hemidystonia, hemiathetosis, epilepsia-partialis-continua and mental decline. Imaging shows unilateral hemispheric brain atrophy. Here we describe a unique case of a 15-year-old Pakistani girl with severe immune mediated brain disorder characterized by unilateral hemispheric atrophy,progressive neurological dysfunction and intractable seizures. Literature on Rasmussen’s encephalitis following is sporadic with very few publications. This clinical entity should be kept in mind when a patient presents with intractable refractory seizures. Early recognition and treatment is beneficial to prevent adverse outcomes.
Shahzad, Waleed; Hassan, Muhammad; Rajput, Haris Majid; Inayat, Tehmina; Khan, Naveed Ullah; and Badshah, Mazhar
"A Rare Case of Epilepsia Partialis Continua Secondary to Rasmussen’s Encephalitis,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 16:
4, Article 4.
Available at: https://ecommons.aku.edu/pjns/vol16/iss4/4