A young boy with no premorbids was admitted with fever, fits and psychosis. His initial investigations including cerebrospinal fluid (CSF) routine examination, electroencephalogram(EEG) and MRI brain with contrast were normal. His autoimmune encephalitis panel revealed positive voltage gated potassium channel(VGKC) antibodies, anti -leucine rich glioma inactivated 1 antibody (LG1) group and was give five doses of methylprednisolone and five sessions of plasmapheresis. Psychiatric symptoms took one month to respond. He had a complete recovery. Autoimmune limbic encephalitis should be diagnosed promptly in young patient with fit, psychosis and a high index of suspicion should be kept as initial work up including MRI brain with contrast, EEG and CSF examination can be normal in such patients.
Niazi, Farheen; Iftikhar, Madeeha; Ali, Rizwan; and Aziz, Tahir
"Vgkc antibody (anti lg1) associated limbic Encephalitis in a young adult with full Recovery.,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 14:
2, Article 1.
Available at: https://ecommons.aku.edu/pjns/vol14/iss2/1