Use of novel oral anticoagulants for Treatment of cerebral venous sinus Thrombosis: a case series and follow up

Authors

Rizwana Shahid, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
Noman Ishaque, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
Aishah Albakr, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
Nourah Abdulaziz AlKhaldi, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
Feras Abdulsalam, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
Abdullah Alsulaiman, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia

Document Type

Original Article

Abstract

Thrombosis of cerebral venous sinuses and/or cortical veins (CVST) is an infrequent type of stroke for which anticoagulation is considered standard of treatment. However, 40% of CVST patients have evidence of parenchymal changes like edema or haemorrhage on neuroimaging which complicates use of anticoagulation in such cases. Therefore, Novel Oral Anticoagulants (NOACs) are recently being used for treatment of CVST as they are associated with half the risk of intracerebral haemorrhage as caused by vitamin K antagonist. Case reports and case series have reported use of NOACs in CVST with good outcomes both clinically and radiologically. We report use of NOACs in five cases of CVST without any worsening or recurrence of symptoms or complication on follow up.

Recommended Citation

Shahid, Rizwana; Ishaque, Noman; Albakr, Aishah; AlKhaldi, Nourah Abdulaziz; Abdulsalam, Feras; and Alsulaiman, Abdullah (2019) "Use of novel oral anticoagulants for Treatment of cerebral venous sinus Thrombosis: a case series and follow up," Pakistan Journal of Neurological Sciences (PJNS): Vol. 14: Iss. 1, Article 5.
Available at: https://ecommons.aku.edu/pjns/vol14/iss1/5