Dopamine responsive dystonia (DRD) is a dystonic syndrome of childhood, usually affecting gait. It presents with walking difficulties, spasticity or dystonia with a characteristic diurnal variation and MRI brain scan is normal in it. It may however develop into Parkinsonism later, which shows dramatic therapeutic response to levodopa. A 25 year old lady presented with difficulty in walking along with weakness and stiffness of both legs at Neurology OPD of Chandka Medical College Hospital,Larkana. After reaching at proper diagnosis of DRD, treatment was started. As a result of which, she showed dramatic improvement and was able to return back to her routine life.
Pechuho, Samar Iltaf; Soomro, Abdul Rahman; Siddiqui, Alam Ibrahim; Pechuho, Tufail Ahmed; and Gopang, Imran Ali
"Dopamine Responsive Dystonia(DRD) in a 25 Year Old Lady,"
Pakistan Journal of Neurological Sciences (PJNS): Vol. 12:
4, Article 10.
Available at: https://ecommons.aku.edu/pjns/vol12/iss4/10