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Document Type

Original Article

Abstract

Spontaneous intracerebral hemorrhage (ICH) accounts for 8-13% of all strokes and is associated with a high mortality and morbidity. Western studies have identified various clinical and radiological factors which help in predicting outcome in patients with spontaneous ICH. Materials and methods: A consecutive series of 100 patients diagnosed with spontaneous ICH admitted to the neurology department were enrolled from 1stJanuary to 30th June, 2014.Radiological parameters on CT brain (plain) were recorded. In-hospital outcome was measured at the end of 7 days of hospital stay in terms of survival or mortality. Different radiological parameters and their effect on outcome were compared by using Chi square test. Multivariate logistic regression analysis was performed to find independent predictors of mortality with a “p” value of < 0.05 indicating statistical significance. Results: The mean age was 47.95 years with SD ± 1.560, with a male preponderance (56%). Of the total cohort, 34% patients expired and 66% survived at the end of 1 week. On univariate analysis age, gender and ICH location had p value >0.05 whereas hematoma volume, presence of IV extension, midline shift and hydrocephalus had p value <0.05. On multivariate logistic regression analysis only higher baseline hematoma volume was an independent predictor of mortality (p=0.00). Among 66 survivors, 44% had moderately severe to severe disability with mRS 4 and 5 at the time of discharge. Conclusion-Intracerebral hemorrhage is associated with high in-hospital mortality and long-term severe disability. Larger baseline hematoma volume was an independent predictor of mortality in this study.

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