Document Type

Original Article


Depression is quite prevalent in patients with chronic kidney disease. Knowing the frequency of depression in such patients and its association with different variables may be helpful in devising strategies for better and timely management of such patients in our setup. Materials and methods: This cross sectional study was conducted by recruiting 315 patients of either gender, ≥ 18 years of age with chronic kidney disease (CKD) and receiving care at Pakistan Institute of Medical Sciences, Islamabad. Patients were divided into two groups; group A: pre-dialysis and group B: dialysis (End Stage Renal Disease). Prevalence of depression in CKD and dialysis group and its association with gender, level of formal education and socioeconomic status was evaluated using descriptive statistics and chi-square test. Results: Out of 204 (100%) patients in group B, 171 (83.8%) patients had depression while in group A, 68 (61.3%) out of 111 (100%) patients were depressed. The prevalence of depression in all stages of CKD combined was 75.87 % (239 out of 315) and that in dialysis group was 83.82% (171 out of 204). Frequency of depression was significantly higher in the dialysis group (p=0.01). Those with higher level of education less commonly suffered from depression (p=0.01). No such association was found with gender (p=0.68) or socioeconomic status (p=0.12).Conclusion: Frequency of depression is significantly higher in dialysis dependent CKD patients with an overall prevalence of 75.87% in CKD and 83.82% in dialysis dependent ones. Higher level of formal education positively affects the outcome while gender and socioeconomic class have no significant association.

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