Assessment and validation of syndromic case definitions for respiratory syncytial virus testing in a low resource population
Women and Child Health; Paediatrics and Child Health
Standardized case definitions are needed in decision-making regarding respiratory syncytial virus control strategies, including vaccine evaluation. A syndromic case definition comprising of "wheeze or apnea or cyanosis" could be useful for community-based surveillance of moderate respiratory syncytial virus infection among young infants particularly in resource-limited settings. However, this definition showed modest specificity (29.2%-49.6%), indicating that community-based surveillance may need augmentation with other data.
Pediatric Infectious Disease Journal
Omer, S. B.,
Guterman, L. B.,
Allen, K. E.,
(2019). Assessment and validation of syndromic case definitions for respiratory syncytial virus testing in a low resource population. Pediatric Infectious Disease Journal, 38(3), e57-e59.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_women_childhealth_paediatr/874