Cardiopulmonary bypass surgery has been linked with a number of postoperative complications. One of the frequently reported physiological alterations is the relative diuresis seen in the immediate post-op period. Rarely reported though is the development of full-blown diabetes insipidus in such patients. The etiology is unknown and has only been hypothesized in the past. We present the clinical course of a 54 year old male who developed transient diabetes insipidus post bypass surgery with subsequent recovery following exogenous vasopressin administration. The physiological alteration leading to the development of diabetes insipidus in a small fraction of bypass patients remains unknown. We propose that the variation in natriuretic peptide levels in the post-bypass period could account for the transient event.
Journal of Pakistan Medical Association
(2005). A case of transient diabetes insipidus following cardiopulmonary bypass. Journal of Pakistan Medical Association, 55(12), 565-566.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_surg_cardiothoracic/130
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