Sonographic evaluation of fetal abnormalities in a baloch population cohort

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Objective: To determine the sonographic frequency and spectrum of fetal abnormalities in a cohort of baloch population presenting at civil hospital karachi
Design: An observational study.
Duration and setting: Radiology department, duhs/chk from august 1999 to june 2001 and front october 2002 to december 2004.
Methodology: 1507 pregnant ladies of baloch racial origin registered with antenatal clinic and delivered at labor room chk during the study period were enrolled.+ level 11 screening antenatal ultrasound was carried out and findings were recorded the new barns were followed up for confirmation of diagnosed anomaly, checking if an anomaly was missed on ultrasound and definitive diagnosis and treatment.
Results: Out of 1507 cases, anomalies were detected in 25 cases (1.6%). hydrops fetalis was seen in 15 (60%), central nervous system (cns) anomalies in 07 (28%) and alimentary tract (git) anomalies were seen in 03 (6%). there were two cardiovascular anomalies which were missed on ultrasound including a small septum secundum type ventricular septal defect and other being a patentductus arteriosus.
Conclusion: The population under study had hydrops fetalis as the commonest antenatally detected anomaly followed by cns and gjt anomalies. cardiovascular anomalies which were mimicking a physiological variation are more likely to be missed.

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