Involvement of bone marrow with intravascular large B-cell lymphoma.
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of extranodal large B-cell lymphoma characterized by a selective proliferation of lymphoma cells within the lumina of vessels. We report a case of an 86-year-old man who presented with fever, shortness of breath and altered mental status. The diagnosis of IVLBCL was confirmed on a bone trephine biopsy that revealed positivity of CD20 and PAX5 immunohistochemical staining of lymphoma cells confined within the lumina of vessels. The Patient had a rapidly deteriorating clinical course with a fatal outcome even before the specific treatment for the underlying disease was commenced.
Hematology/Oncology and Stem Cell Therapy
(2010). Involvement of bone marrow with intravascular large B-cell lymphoma.. Hematology/Oncology and Stem Cell Therapy, 3(1), 39-41.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_radiat_oncol/12