Pathology and Microbiology; Haematology/Oncology
We describe case of a 40 year old male, who went on to developed systemic amyloidosis 3 years after the diagnosis of chronic renal failure. The diagnosis of systemic amyloidosis was suspected upon a routine examination of periheral blood film showing features of hyposlenism. We would like to highlight the importance of examination of pheripheral blood film in patients with renal failure for the diagnosis of extensive systemic amyloidosis which occasionally leads to functional hyposplenism, recognized by the presence of abnormal red cell morphology and reduced splenic uptake on isotope scan1.
Journal of Pakistan Medical Association
(2001). Impaired splenic function in systemic amyloidosis: diagnostic importance of peripheral blood film. Journal of Pakistan Medical Association.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/569