Pathology and Microbiology; Haematology/Oncology
Waldenstrom's macroglobulinemia (WM) is a rare condition, accounting for approximately 2% of haematologic malignancies. The most common causes of death in these patients are progression of the malignant lymphoproliferative process, infection and cardiac failure. Acute leukemia is a rare event in the clinical course of WM. A number of case reports have documented the development of terminal acute leukemia in patients with WM following prolonged chemotherapy.
Journal of Pakistan Medical Association
(2006). Waldenstrom's macroglobulinemia terminating in acute myeloid leukemia. Journal of Pakistan Medical Association, 56(6), 291-292.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/549