Isolated cryptococcal osteomyelitis in an immunocompetent patient

Irfan Qadir, Aga Khan University
Farheen Ali, Aga Khan University
Umair Z. Malik, Aga Khan University
Masood Umer, Aga Khan University


Cryptococcosis is a rare infection in HIV-negative individuals. While the lungs and the central nervous system are most commonly infected, skeletal cryptococcosis is uncommon and isolated osteomyelitis due to Cryptococcus neoformans is quite rare. To our knowledge, only 47 cases of isolated cryptococcal osteomyelitis have been reported from 1974 to 2005. We report a case of isolated cryptococcal osteomyelitis in an immunocompetent Patient, who received 12 weeks of fluconazole with complete recovery.