Objective: A pre-tested questionnaire-based, retrospective study to highlight the causative factors, mode of presentation, complications and outcome of patients with Stevens Johnson syndrome.SETTING: Aga Khan University Hospital over a 10 year period.Methods: All case records with a diagnosis of Steven Johnson Syndrome in the period 1990 to 2000 were retrospectively reviewed. Data was retrieved on a comprehensive questionnaire. The demographic variatbles and drugs taken within the previous 21 days were noted. Date analysis was done by Epi-Info Version 6.0.Results: Of the 101 studied patient files, the most common offender was found to be the Penicillins as a group and Sulfadoxine-Pyrimethamine (Fansidar) when considering all drugs individually. Most common complications included electrolyte disturbances (13.9%) and congestive heart failure (6.9%). Mortality rate was high at 10.1%.CONCLUSION: SJS was found to be a rare condition but having a mortality rate of 10.1%. As it can be induced by a large number of drugs, caution should be practiced while prescribing.
Journal of Pakistan Medical Association
Ahmed, Y. I.,
Majid, T. H.,
(2004). Stevens Johnson syndrome in Pakistan: a ten-year survey. Journal of Pakistan Medical Association, 54(6), 312-315.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_med_intern_med/97
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