Vitamin E deficiency and platelet functional defect in a jaundiced infant
Document Type
Article
Department
Haematology/Oncology
Abstract
A 16-month-old infant with hepatic fibrosis, cholestasis, and chronic jaundice had signs of vitamin E deficiency, including mild acanthocytosis, thrombocytosis, increased peroxide haemolysis, and absent serum vitamin E. Abormal prothrombin consumption and platelet restocetin aggregation suggested the presence of defective platelet function, and correction studies indicated that this was due to a plasma defect. The abnormality was corrected by treatment with vitamin E, and the findings suggest a possible role of this vitamin in platelet reactions.
Publication (Name of Journal)
British Medical Journal
Recommended Citation
Khurshid, M.,
Lee, T.,
Peake, I.,
Bloom, A.
(1975). Vitamin E deficiency and platelet functional defect in a jaundiced infant. British Medical Journal, 4(5987), 19-21.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_med_haematol_oncol/29