Document Type
Report
Department
Gastroenterology
Abstract
Hyper Immunoglobulin E syndrome also called Job's or Buckley Syndrome is a rare primary immunodeficiency disease characterized by elevated serum IgE levels (> 2000 IU/ml), recurrent infections and eosinophilia. Other features include coarse facies and non-immunologic abnormalities of the dentition, bones, vasculature and connective tissues. We are reporting a case of a twenty four years old male with coarse facies who presented with severe pallor and upper gastrointestinal bleeding. Investigations revealed markedly elevated serum IgE levels (11,800 IU/ml), severe anaemia, esophageoduodenal erosions, Helicobacter pylori (H. pylori) gastritis and oro-esophageal candidiasis.
Publication (Name of Journal)
Journal of Pakistan Medical Association
Recommended Citation
Tasneem, A. A.,
Sarfaraz, S.,
Hassan, S. M.,
Luck, N. H.,
Anis, S.,
Abbas, Z.
(2013). Job's syndrome with an atypical presentation. Journal of Pakistan Medical Association, 63(11), 1427-1429.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_med_gastroenterol/204
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.