Emergency Medicine; Department of Medicine; Centre for Innovation in Medical Education
Neonatal Purpura Fulminans is a rare and fatal disorder associated with perivascular haemorrhage and disseminated intravascular coagulation. Early clinical recognition, timely investigation and treatment is utmost important. A 6 days old baby boy was brought to emergency with blackish ulcers all over the body. Initially these were over the feet and scalp but later appeared on the abdomen. On examination, child was vitally stable, mildly icteric and had multiple erythematous large bullous blackish lesions on scalp, lower abdomen, perineum, back and soles. Neonatal reflexes and systemic examination was normal. Laboratory investigations showed normal CBC, PT/APTT and Protein S level while Protein C and Antithrombin III levels were low. Neonatal Purpura Fulminans is a life threatening condition and family screening is also mandatory for early recognition of disease in the siblings.
Journal of Pakistan Medical Association
Kazi, G. I.,
Khan, I. Q.
(2018). Neonatal Purpura Fulminans, a rare genetic disorder due to protein C deficiency: A case report.. Journal of Pakistan Medical Association, 68(3), 463-465.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_emerg_med/214
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