Title

Primary Amoebic Meningoencephalitis Preventive Nose Plugs: Prophylaxis Against Naegleria fowleri

Document Type

Article

Department

Biological and Biomedical Sciences

Abstract

Naegleria fowleri is a free-living amoeba; it is a protist pathogen that is known to cause a fatal encephalitis in humans known as “primary amoebic meningoencephalitis” (PAM). The peak season for the cases admitted to the hospital is in the summers, and all the reported cases have a history of exposure to the warm waters. Mostly, PAM is reported in recent swimmers and people who perform ablution and/or nasal cleansing. Much has been done for vaccination and treatment without any success in past 60 years, but the mortality has remained 99%. Here, we propose a prophylaxis for this disease by introducing a device “Naegleriopel.” This device is noninvasive and requires insertion into the nostrils at times of swimming or water sports related activities. This device, made up of synthetic plastic or silicone, could be adapted to the contours of the interior of the nose. It is expected to reduce the sporadic and seasonal incidences of PAM.

Publication

ASME Journal of Medical Devices