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Objective: Fluid balance remains a highly controversial topic in the critical care field, and there is no consensus about the amount of fluid required by critically ill patients.In this study, the objective was to find the relationship between fluid balance and in hospital mortality in critically ill surgical patients.Our secondary objective was to identify the association between use of colloid and acute kidney injury and use of blood products and development of ARDS.
Study Design: The medical records of adult patients admitted to a surgical intensive care unit (ICU) >48 hours, from Aug 2014 toFeb 2016 (18 months) were reviewed retrospectively.
Place and Duration of Study: The study was conducted in the surgical intensive care unit of a tertiary care hospital.Medical records of 18 months from Aug 2014 toFeb 2016 were reviewed.
Material and Methods: Sampling technique was convenience sampling. A total of 100 patients met the inclusion criteria. Abstracted dataof patients admitted to surgical intensive care included body mass index, Acute physiology and chronic health evaluation (APACHE)-II scores, fluid balance during first 5 days of ICU stay, length of ICU stay andin hospitalmortality. All statistical analysis was performed using statistical packages for social science version 19 (SPSS Inc., Chicago, IL). Frequency and percentage werecomputed for qualitative observation and wereanalyze by chi-square test. Mean (±Standard deviation) andmedian (IQR) were presented for quantitative variables and analyze by independent sample t-test and Mann-Whitney test. Normality of quantitative data wasalso be checked by Kolmogorov-Smirnov test. Statistically significantresults had a p-value less than0.05.
Results: A total of 100 patients fulfilled the inclusion criteria. The average age of patients was 44.08±18.14 (years), BMI (kg/m2) 27.84±5.56 and APACHE II Score 17.28±6.96. The in hospital mortality was 26%, median length of ICU and hospitalstay was 6.91 ±4.07 and 14.74 ±7.78 days. In non-survivors fluid balance was significantly positive on 2nd, 3rd, 4th and 5thday of SICU (p-value: 0.005, 0.0005 and 0.024), APACHE II score (pConclusion: Positive fluidbalance, high APACHE II score and acute kidney injury is significantly associated with hospital mortality of non-cardiac surgical ICU patients.

Publication (Name of Journal)

Pakistan Armed Forces Medical Journal

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Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.