Date of Award
12-5-2022
Degree Type
Thesis
Degree Name
Master of Science in Nursing (MScN)
First Advisor
Dr. Rubina Barolia
Second Advisor
Ms. Ambreen Gowani
Third Advisor
Dr. Javed Majid Tai
Department
School of Nursing and Midwifery, Pakistan
Abstract
Background: Heart Failure (HF) is a significant universal issue. Its prevalence has drastically increased due to an upsurge of risk factors, such as aging, elevated blood pressure, and ischemic heart disease (IHD). Adherence to the medication regimen is the most important self-care behavior for HF management. While, the level and pattern of medication adherence are well known in the high-income countries, there is little information about medication adherence and its associated factors among HF patients in Pakistan.
Purpose: To assess the level of medication adherence and its associated factors among patients with HF in Karachi, Pakistan.
Method: The study used a prospective cohort study design. A non-probability consecutive sampling method was used to recruit 124 HF patients. Medication adherence was assessed at baseline, four weeks (time 1), and eight weeks (time 2), through the General Medication Adherence Scale (GMAS).
Findings: The overall, medication adherence increased over time from 89% at baseline to 90% at four weeks and approximately 91% at eight weeks. Moreover, subgroup analysis indicates that the key reasons for nonadherence were patient behavior such as remembering to take medication, forgetfulness, busy schedule, feeling well, and side effects (10.48%), and financial constraints (8.06%). Whereas, additional disease and pill burden of medication did not contribute to medication nonadherence. In addition, income was a substantial predictor of medication adherence among heart failure patients.
Conclusion: The results of the present study provide important insights into medication adherence in the Pakistani population. Patient behavior and financial constraints are the main reasons for nonadherence. These issues need to be adequately addressed to improve overall patient outcomes. Future longitudinal studies are needed to test these results in a large population or among impoverished societies.
First Page
1
Last Page
50
Recommended Citation
Majeed, I. A.
(2022). Adherence to medication and its associated factors among patients with heart failure in a tertiary care hospital, Karachi, Pakistan: a prospective study. , 1-50.
Available at:
https://ecommons.aku.edu/etd_pk_sonam_mscn/23