Elastography Evaluation of Liver Fibrosis in Patients with Hepatitis B

Document Type



Imaging and Diagnostic Radiology (East Africa)


Background: The presence and progression of hepatic (liver) fibrosis into cirrhosis is a prognostic variable having impact on survival in people with alcoholic liver disease. Transient elastography (TE) is a non-invasive method for assessing and staging hepatic fibrosis. Objectives: To determine the diagnostic accuracy of TE for diagnosis and staging hepatic fibrosis in people with alcoholic liver disease when compared with liver biopsy (LB). Selection Criteria: Diagnostic cohort and diagnostic case-control study designs that assessed hepatic fibrosis in participants with alcoholic liver disease with TE and LB, irrespective of language or publication status. Data Collection and Analysis: We followed the guidelines in the draft Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. Main Results: Five retrospective and nine prospective cohort studies with 834 participants provided data for the review …

Publication (Name of Journal)

Ultrasound in Medicine and Biology