Effect of salt taste threshold on cardiovascular response to isotonic exercise in young adults

Document Type



Biomedical Sciences (East Africa)


Increased salt intake among persons with high salt taste threshold may lead to exercise-induced hypertension and eventually arterial hypertension. Salt sensitivity has been demonstrated among our populace. This study was designed to investigate the effect of salt taste threshold (STT) on cardiovascular response to exercise. The study protocol was carried out in accordance with the Declaration of Helsinki. Forty-seven normotensive individuals participated in the study after giving informed consent. Baseline blood pressure, BP (mmHg) and heart rate, HR (beats/min) were determined in all subjects. Salt taste threshold (STT) was determined by making subjects taste increasing concentrations (15mmol/L–105 mmol/L) of NaCl prior to exercise and subjects were divided into Low salt tasters (LST,/L) and high salt tasters (HST, >60 mmol/L). Each participant completed 6 minutes of isotonic (Havard Step Test) exercise. Data were analyzed using Student t test with GraphPad Prism version 5. Significance was accepted at p0.05) from that of LSTs. Similarly, the %Δ in HR response of HST to isotonic exercise was not different (p=0.898) from that of LSTs. Plasma sodium (7.42 ±0.42 mmol/L) was higher in HSTs (p


This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Federation of American Societies for Experimental Biology