Risk of restless legs syndrome in low socioeconomic rheumatoidarthritis patients

Document Type



Internal Medicine (East Africa)



Our aim was to determine the frequency ofrestless leg syndrome (RLS) in rheumatoid arthritis (RA)patients from a low socioeconomic area of Pakistan andcompare results with a control group to evaluate the effectof variables on RLS patients

.Methods A clinical observational study was carried outon 240 RA patients form low socioeconomic group. Con-trols (n=210) were frequency-matched by age group tothe RA patients. We evaluated the presence of RLS andcollected information on characteristics believed to becorrelated with RLS in the general population. Multiplelogistic regression models were used to study the associa-tion between RLS and other risk factors such as age,smoking status, and obesity

.Results Among all rheumatic patients seen at our rheu-matology clinic, 70.8 % were women. Our study showsthat 20 % of RA patients were suffering from RLS com-pared with 10 % of the control group with other rheumaticdiseases. Multivariate logistic regression adjusted for age,obesity, and smoking also showed that women with RAwere more likely to have RLS than control patients.


This work was published before the author joined Aga Khan University.

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