This collection showcases publications on the Coronavirus (COVID-19) by faculty and researchers at Aga Khan University.

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Submissions from 2021

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Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase, Syed Hani Abidi, Nahlah Makki Almansour, Daulet Amerzhanov, Khaled S. Allemailem, Wardah Rafaqat, Mahmoud A A. Ibrahim, Philip la Fleur, Martin Lukac, and Syed Ali

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The Conundrum of Low COVID-19 Mortality Burden in sub-Saharan Africa: Myth or Reality?, Janica Adams, Mary J. MacKenzie, Adeladza Kofi Amegah, Alex Ezeh, Muktar A. Gadanya, Akinyinka Omigbodun, Ahmed Sarki, Paul Thistle, Abdhalah K. Ziraba, Saverio Stranges, and Michael Silverman

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Evaluation of serum ferritin for prediction of severity and mortality in COVID-19- A cross sectional study, Sibtain Ahmed, Zeeshan Ansar Ahmed, Imran Siddiqui, Naveed Haroon Rashid, Maheen Mansoor, and Lena Jafri

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Nutritional perspectives for the prevention and mitigation of COVID-19, Saeed Akhtar, Jai K. Das, Tariq Ismail, Muqeet Wahid, Wisha Saeed, and Zulfiqar Ahmed Bhutta

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CardiOvaScular Mechanisms In Covid-19: methodology of a prospective observational multimodality imaging study (COSMIC-19 study), Shirjel Alam, Anoop Shah, Kevin Onyinkwa, Edward Nganga, Samuel Gitau, Khalid Makhdomi, Michael Chung, and Sudhir Vinayak

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When COVID-19 enters in a community setting: An exploratory qualitative study of community perspectives on COVID-19 affecting mental well-being, Naureen Akber Ali, Anam Shahil Feroz, Noshaba Akber, Rida Feroz, Salima Nazim Meghani, and Sarah Saleem

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Acuity level of care as a predictor of case fatality and prolonged hospital stay in patients with COVID-19: A hospital-based observational follow-up study from Pakistan, Aysha Almas, Zain Mushtaq, and Jette Moller

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Online medical education and examinations during COVID-19: Perspectives of a teaching associate, Syed Mujtaba Baqir and Fatima Mustansir

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Violence against healthcare workers during the COVID-19 pandemic: A review of incidents from a lower-middle-income country, Omaima Anis Bhatti, Hareem Rauf, Namrah Aziz, Russell Seth Martins, and Javaid Ahmed Khan

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Beyond the numbers: Understanding the diversity of covid-19 epidemiology and response in south Asia, Zulfiqar Ahmed Bhutta, Sameen Siddiqi, Assad Hafeez, Muhammad Islam, Samiran Nundy, Firdausi Qadri, and Faisal Sultan

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COVID-19 and adult acute lymphoblastic leukemia: Presentation and management, Ayesha Butt and Natasha Bahadur Ali

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A Continental Survey on the Impact of COVID-19 on Neurosurgical Training in Africa, Beverly Cheserem, Ignatius N. Esene, Muhammad Raji Mahmud, Kazadi Kalangu, Samuila Sanoussi, Aaron Musara, Nasser M. F. El-Ghandour, Graham Fieggen, and Mahmood Qureshi

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Unilateral optic neuritis associated with SARS-CoV-2 infection: A rare complication, Kitson Deane, Azza Sarfraz, Zouina Sarfraz, Dhiviyan Valentine, Abidemi Rachael Idowu, and Vincent Sanchez

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Correlation of severity of COVID-19 disease with gastrointestinal manifestations and liver injury - A north Brooklyn community hospital experience: A retrospective cohort study, Kitson Deane, Ajay Singh, Azza Sarfraz, Zouina Sarfraz, Lyam Ciccone, Beishi Zheng, Arslan Afzal, Gulam Khan, Giovanna Rodriguez, and Gul Bahtiyar

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Oral manifestations of Covid-19-A literature review, Huma Farid, Madiha Khan, Shizrah Jamal, and Rabia Ghafoor

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Building better tuberculosis control systems in a post-COVID world: Learning from Pakistan during the COVID-19 pandemic, Razia Fatima, Nasim Akhtar, Aashifa Yaqoob, Anthony D. Harries, and Mishal S. Khan

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Equipping community health workers with digital tools for pandemic response in LMICs, Anam Shahil Feroz, Adeel Khoja, and Sarah Saleem

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COVID-19, community trials, and inclusion, Paramjit S. Gill, Shoba Poduval, Jarnail S. Thakur, and Romaina Iqbal

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Cerebral venous thrombosis associated with COVID-19 infection: An observational, multicenter study, Sajid Hameed, Mohammad Wasay, Bashir A. Soomro, Ossama Mansour, Foad Abd-Allah, Tianming Tu, Raja Farhat, Naila Shahbaz, Husnain Hashim, and Wasim Alamgir

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Mobilising evidence, data, and resources to achieve global maternal and child undernutrition targets and the sustainable development goals: An agenda for action, Rebecca A. Heidkamp, Ellen Piwoz, Stuart Gillespie, Emily C. Keats, Mary R. D'Alimonte, Purnima Menon, Jai K. Das, Augustin Flory, Jack W. Clift, and Zulfiqar Ahmed Bhutta

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Knowledge, attitudes, and practices of the Pakistani population regarding facemasks during the covid-19 pandemic, Rubina Izhar, Samia Husain, Muhammad Ahmad Tahir, Sonia Husain, and Saba Hussain

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Diagnostic dilemma in COVID-19-associated pulmonary aspergillosis, Kauser Jabeen, Joveria Farooqi, Muhammad Irfan, Syed Ahsan Ali, and David W. Denning

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The association of chest radiographic findings and severity scoring with clinical outcomes in patients with COVID-19 presenting to the emergency department of a tertiary care hospital in Pakistan, Raima Kaleemi, Kiran Hilal, Ainan Arshad, Russell Seth Martins, Avinash Nankani, Tanveer Ul Haq, Sundas Basharat, and Zeeshan Ansar

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Stress and anxiety among dental practitioners during the COVID-19 pandemic: A cross-sectional survey, Adeel Tahir Kamal, Rashna Hoshang Sukhia, Dinaz Ghandhi, and Hoshang Rumi Sukhia

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COVID-19 and mental well-being of nurses in a tertiary facility in Kenya, Sayed Karar, Jasmit Shah, and Zohray Talib

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The COVID-19 pandemic: A catalyst for creativity and collaboration for online learning and work-based higher education systems and processes, Tashmin Khamis, Azra Naseem, Anil Khamis, and Pammla Petrucka

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Vitamin D and COVID-19: Is there a role?, Aysha Habib Khan, Noreen Nasir, Nosheen Nasir, Quratulain Maha, and Rehana Rehman

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Imaging patterns of encephalopathy in patients with COVID-19, Kumail Khandwala, Fatima Mubarak, and Nadeem Ahmad

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Rethinking vaccine hesitancy among minority groups, Mishal S. Khan, Sameen A Mohsin Ali, Addy Adelaine, and Abraar Karan

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Supporting front-line postgraduate medical trainees during the COVID-19 pandemic: A checklist for organisations, Muhammad Rizwan Khan, Zainab Samad, and Adil H. Haider

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Role of awake prone positioning in patients with moderate-to-severe COVID-19: An experience from a developing country, Iffat Khanum, Fatima Samar, Fatimah Yousuf, Safia Awan, Adil Aziz, Kiren Habib, Nosheen Nasir, Syed Faisal Mahmood, and Bushra Jamil

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The COVID-19 pandemic: An opportunity to strengthen health systems in Afghanistan, Umerdad Khudadad, Najibullah Safi, Wafa Aftab, Asrar Ali, and Sameen Siddiqi

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International Prospective Registry of Acute Coronary Syndromes in Patients With COVID-19, Thomas A. Kite, Peter F. Ludman, Chris P. Gale, Adriano Caixeta, Jacques Mansourati, Manel Sabate, Pilar Jimenez-Quevedo, Luciano Candilio, Parham Sadeghipour, and Mzee Ngunga

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Mental Disorders Among Health Care Workers at the Early Phase of COVID-19 Pandemic in Kenya; Findings of an Online Descriptive Survey, Edith Kamaru Kwobah, Ann Mwangi, Kirtika Patel, Thomas Mwogi, Robert Kiptoo, and Lukoye Atwoli

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A living WHO guideline on drugs to prevent covid-19, François Lamontagne, Thomas Agoritsas, Reed Siemieniuk, Bram Rochwerg, Jessica Bartoszk, Lisa Askie Lisa Askie, Helen Macdonald, Wagdy Amin, Frederique Jacquerioz Bausch, and Saniya Sabzwari

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Teleneurology based management of infantile spasms during COVID-19 pandemic: A consensus report by the south Asia allied west syndrome research group, Priyanka Madaan, Jitendra Kumar Sahu, Jithangi Wanigasinghe, Kanij Fatema, Kyaw Linn, Mimi Lhamu Mynak, Nicolás Garófalo Gómez, Pauline Samia, Prakash Poudel, and Prem Chand

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The Impact of COVID-19 on Neurosurgical Services in Africa, Muhammad Raji Mahmud, Beverly Cheserem, Ignatius N. Esene, Kazadi Kalangu, Samuila Sanoussi, Aaron Musara, Nasser M.F. El-Ghandour, Graham Fieggen, and Mahmood Qureshi

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Mental health of children and adolescents amidst COVID-19 and past pandemics: A rapid systematic review, Salima Meherali, Neelam Punjani, Samantha Louie-Poon, Komal Abdul Rahim, Jai K. Das, Rehana A. Salam, and Zohra S. Lassi

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Disease surveillance for the COVID-19 era: Time for bold changes, Oliver W. Morgan, Ximena Aguilera, Andrea Ammon, John Amuasi, Ibrahima Socé Fall, Tom Frieden, David Heymann, Chikwe Ihekweazu, Eun-Kyeong Jeong, and Farah Naz Qamar

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Rebuilding trust on routine immunization in era of COVID-19 fear-role that civil society organizations can play hands-in-hand with immunization program, Ameer Muhammad, Daniyaal Ahmad, Eleze Tariq, and Yasir Shafiq

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Clinical characteristics and outcomes of COVID-19: Experience at a major tertiary care center in Pakistan, Nosheen Nasir, Kiren Habib, Iffat Khanum, Naveera Khan, Zehra Abdul Muhammad, and Syed Faisal Mahmood

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Risk factors for bacterial infections in patients with moderate to severe COVID-19: A case-control study, Nosheen Nasir, Fazal Ur Rehman, and Syed Furrukh Omair

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Serial population-based serosurveys for COVID-19 in two neighbourhoods of Karachi, Pakistan, Muhammad Imran Nisar, Nadia Ansari, Farah Khalid, Mashal Amin, Hamna Shahbaz, Aneeta Hotwani, Najeeb Rehman, Usma Mehmood, Arjumand Rizvi, Junaid Iqbal, Ali Faisal Saleem, and Fyezah Jehan

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COVID-19 pandemic: From origins to outcomes. A comprehensive review of viral pathogenesis, clinical manifestations, diagnostic evaluation, and management, RohanKumar Ochani, Ameema Asad, Farah Yasmin, Shehryar Shaikh, Hiba Khalid, Simran Batra, Muhammad Rizwan Sohail, Syed Faisal Mahmood, Rajkumar Ochani, and Mohammad Hussham Arshad

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How COVID-19 has fundamentally changed clinical research in global health, Jay J H. Park, Robin Mogg, Gerald E. Smith, Etheldreda Nakimuli-Mpungu, Fyezah Jehan, Craig R. Rayner, Jeanine Condo, Eric H. Decloedt, Jean B. Nachega, Gilmar Reis, and Edward J. Mills

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Suicide trends in the early months of the COVID-19 pandemic: An interrupted time-series analysis of preliminary data from 21 countries, Jane Pirkis, Ann John, Sangsoo Shin, Marcos DelPozo-Banos, Vikas Arya, Pablo Analuisa-Aguilar, Louis Appleby, Ella Arensman, Jason Bantjes, and Murad M. Khan

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Implications for schools reopening during the second wave of COVID-19 in Pakistan, Nousheen Pradhan and Kashmira Nanji

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Sex hormones, autoimmunity and gender disparity in COVID-19, Hussain Ahmed Raza, Parikshit Sen, Omaima Anis Bhatti, and Latika Gupta

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COVID-19, hydroxychloroquine and sudden cardiac death: Implications for clinical practice in patients with rheumatic diseases, Hussain Ahmed Raza, Javeria Tariq, Vikas Agarwal, and Latika Gupta

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COVID-19 pandemic awareness, attitudes, and practices among the Pakistani general public, Rehana Rehman, Shireen Jawed, Rabiya Ali, Khola Noreen, Mukhtiar Baig, and Javaria Baig

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COVID-19 screening in a healthcare or community setting: complexity of saliva as a specimen for PCR-based testing, Nikhil Shri Sahajpal, Ashis K. Mondal, Allan Njau, Sudha Ananth, Salil Ghamande, Madhuri Hegde, Alka Chaubey, Amyn M. Rojiani, and Ravindra Kolhe

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Understanding and promoting racial diversity in healthcare settings to address disparities in pandemic crisis management, Azza Sarfraz, Zouina Sarfraz, Alanna Barrios, Kuchalambal Agadi, Sindhu Thevuthasan, Krunal Pandav, Manish Kc, Muzna Sarfraz, Pedram Rad, and George Michel

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Tocilizumab and COVID-19: A meta-analysis of 2120 patients with severe disease and implications for clinical trial methodologies, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Hinna Aftab, and Zainab Pervaiz

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Is COVID-19 pushing us to the fifth industrial revolution (Society 5.0)?, Zouina Sarfraz, Azza Sarfraz, Hamza M. Iftikar, and Ramsha Akhund

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Subcutaneous emphysema and pneumomediastinum in patients with COVID-19 disease; case series from a tertiary care hospital in Pakistan, Sher Sethi, Amber Sabeen Ahmed, Sadaf Hanif, Masooma Aqeel, and Ali Bin Sarwar Zubairi

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The novel coronavirus (COVID-19) pandemic and the response in low-to-middle income countries, Hania Shahzad, Fatima Mubarik, and Abida K. Sattar

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Duty versus distributive justice during the COVID-19 pandemic, Sheila Shaibu, Rachel Kimani, Constance Shumba, Rose Maina, Eunice Ndirangu, and Isabel Kambo

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Lateral ST-elevation myocardial infarction after donation of COVID-19 convalescent plasma in a naïve donor, Pirbhat Shams and Fateh Ali Tipoo Sultan

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Exploring equity in health and poverty impacts of control measures for SARS-CoV-2 in six countries, Sedona Sweeney, Theo Prudencio Juhani Capeding, Rosalind Eggo, Maryam Huda, Mark Jit, Don Mudzengi, Nichola R. Naylor, Simon Procter, Matthew Quaife, and Lela Serebryakova

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Safety and efficacy of COVID-19 vaccines in pregnant women with rheumatic diseases: An immunologic perspective, Javeria Tariq and Latika Gupta

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Human emotions during COVID-19: A lens through Kubler-Ross grief theory, Komal Valliani and Farida Bibi Mughal

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Maternal and neonatal morbidity and mortality among pregnant women with and without COVID-19 Infection: The INTERCOVID multinational cohort study, José Villar, Shabina Ariff, Robert B. Gunier, Ramachandran Thiruvengadam, Stephen Rauch, Alexey Kholin, Paola Roggero, Federico Prefumo, Marynéa Silva do Vale, and Zulfiqar Ahmed Bhutta

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COVID-19 pandemic and breast cancer management: A retrospective observational clinical study from Pakistan, Lubna Mushtaque Vohra, Dua Jabeen, Narmeen Asif, and Abdul Ahad

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Comparative analysis of pediatric COVID-19 infection in Southeast Asia, south Asia, Japan, and China, Judith Ju Ming Wong, Qalab Abbas, Soo Lin Chua, Ririe Fachrina Malisie, Kah Min Pon, Tomohiro Katsuta, Hongxing Dang, Pei Chuen Lee, Muralidharan Jayashree, and Quratulain Maha

Submissions from 2020

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Call to action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE), Shahram Abootalebi, Benjamin M. Aertker, Mohammad Sobhan Andalibi, Negar Asdaghi, Ozlem Aykac, M Reza Azarpazhooh, M Cecilia Bahit, Kristian Barlinn, Hamidon Basri, and Mohammad Wasay

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The changing trend of teleconsultations during COVID-19 era at a tertiary facility in Tanzania, Philip Adebayo, Ahmed Jusabani, Murtaza Mukhtar, and Ali Akbar Zehri

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Practice of academic surgical pathology during the COVID-19 pandemic, Zubair Ahmad, Shabina Rahim, Nasir Ud Din, and Arsalan Ahmed

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COVID-19 and liver injury: A systematic review and meta-analysis, Jawad Ahmed, Tehlil Rizwan, Farheen Malik, Raniyah Akhter, Mehreen Malik, Junaid Ahmad, Abdul Wasay Khan, Muhammad A. Chaudhary, and Muhammad Shariq Usman

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Search for rapid and less expensive COVID-19 tests for lower middle-income countries-antigen based immunoassays remains a neglected tool, Sibtain Ahmed

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Trend analysis of lab tests requisitions of COVID-19 prognostic biomarkers at a clinical chemistry reference laboratory-an observational study, Sibtain Ahmed and Farooq Ghani

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Challenges amid COVID-19 times - Review of the changing practices in a clinical chemistry laboratory from a developing country, Sibtain Ahmed, Lena Jafri, Hafsa Majid, Aysha Habib, Farooq Ghani, and Imran Siddiqui

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COVID-19 and the practice of rheumatology in Africa: big changes to services from the shockwave of a pandemic, Richard Oluyinka Akintayo, Akpabio Akpabio, Asgar Kalla, Dzifa Dey, Angela Migowa, Hakeem Olaosebikan, Yasser El Miedany, Rachid Bahiri, Djohra Hadef, and Wafa Hamdi

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COVID-19 pandemic and mitigation strategies: Implications for maternal and child health and nutrition, Nadia Akseer, Goutham Kandru, Emily C. Keats, and Zulfiqar Ahmed Bhutta

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The global impact of COVID-19 on gastrointestinal endoscopy units: An international survey of endoscopists, Mohamed Alboraie, Alejandro Piscoya, Quang Trung Tran, Robin B. Mendelsohn, Amna Subhan Butt, Luciano Lenz, Pezhman Alavinejad, Mohamed H. Emara, Zouhour Samlani, and Ahmed Altonbary

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COVID-19 (Coronavirus) pandemic: Information sources channels for the public health awareness, Muhammad Yousuf Ali Mr and Rubina Bhatti

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Digital technologies applications in the provision of library and information services in health crises, Muhammad Yousuf Ali, Salman Bin Naeem, and Rubina Bhatti

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Maternal mental health amidst the COVID-19 pandemic, Naureen Akber Ali and Anam Feroz

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Telehealth: An important player during the COVID-19 pandemic, Naureen Akber Ali and Adeel Khoja

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Mitigating toxic stress in children affected by conflict and displacement, Anushka Ataullahjan, Muthanna Samara, Theresa S. Betancourt, and Zulfiqar Ahmed Bhutta

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Risk factors for intensive care unit admission and mortality in hospitalized COVID-19 patients, Ahmed Ayaz, Ainan Arshad, Hajra Malik, Haris Ali, Erfan Hussain, and Bushra Jamil

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Can neurotropic free-living amoeba serve as a model to study SARS-CoV-2 pathogenesis?, Abdul Mannan Baig

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Computing the effects of SARS-CoV-2 on respiration regulatory mechanisms in COVID-19, Abdul Mannan Baig

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Covert pathways to the cranial cavity: Could these be potential routes of SARS-CoV-2 to the brain?, Abdul Mannan Baig

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Neurological manifestations in COVID-19 caused by SARS-CoV-2, Abdul Mannan Baig

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Updates on what ACS reported: Emerging evidences of COVID-19 with nervous system involvement, Abdul Mannan Baig

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Ocular COVID-19: Eyes as a reservoir to conceal and spread SARS-CoV-2, Abdul Mannan Baig, Saara Ahmad, Areeba Khaleeq, Hamna Rafique, Shafiqa Rajput, Meher Angez, Ayesha Nasir Hameed, Talha Nawaz, and Preet Katyara

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Evidence of the COVID-19 virus targeting the CNS: Tissue distribution, host-virus interaction, and proposed neurotropic mechanisms, Abdul Mannan Baig, Areeba Khaleeq, Usman Ali, and Hira Syeda

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Elucidation of cellular targets and exploitation of the receptor-binding domain of SARS-CoV-2 for vaccine and monoclonal antibody synthesis, Abdul Mannan Baig, Areeba Khaleeq, and Syeda Hira

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Docking prediction of amantadine in the receptor binding domain of spike protein of SARS-CoV-2, Abdul Mannan Baig, Areeba Khaleeq, and Hira Syeda

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Deleterious outcomes in long-hauler COVID-19: The effects of SARS-CoV-2 on the CNS in chronic COVID syndrome, Abdul Mannan Mannan Baig

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Heralding healthcare professionals: Recognition of neurological deficits in COVID-19, Abdul Mannan Baig and Erin C. Sanders

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Potential neuroinvasive pathways of SARS-CoV-2: Deciphering the spectrum of neurological deficit seen in coronavirus disease 2019 (COVID-19), Abdul Mannan Baig and Erin C. Sanders

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Promoting Positive Birth Experiences: Supporting Pregnant and Lactating Women During the COVID-19 Crisis, Marina Baig, Shelina Bhamani, Zohra Kurji, Lumaan Sheikh, and Rozina Karmaliani

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The COVID-19 intubation and ventilation pathway (CiVP); a commentary, Muhammad Akbar Baig

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The rapid COVID screening (RCS) tool, Muhammad Akbar Baig

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Covid-19 risks and response in South Asia, Zulfiqar Ahmed Bhutta, Buddha Basnyat, Samir Saha, and Ramanan Laxminarayan

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COVID-19, children and non-communicable diseases: Translating evidence into action, Zulfiqar Ahmed Bhutta, Marie Hauerslev, Mychelle Farmer, and Laura Lewis-Watts

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Revisiting child and adolescent health in the context of the sustainable development goals, Zulfiqar Ahmed Bhutta, Kathryn M. Yount, Quique Bassat, and Artur A. Arikainen

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Alcohol consumption and obesity: The hidden scare with COVID-19 severity, Bushra Bilal, Faizan Saleem, and Syeda Sadia Fatima

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COVID-19 in Africa: care and protection for frontline healthcare workers, Matthew F. Chersich, Glenda Gray, Lee Fairlie, Quentin Eichbaum, Susannah Mayhew, Brian Allwood, Rene English, Fiona Scorgie, Stanley Luchters, and Greg Simpson