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Document Type

Original Article

Abstract

Diabetic peripheral neuropathy (DPN) is one of the common complications of diabetes mellitus. Aim: To find out gender based differences in frequency of DM, age at diagnosis of DM and subsequent onset of DPN, duration of DM and DPN and electrophysiological patterns. Methodology: On the basis of non-probability purposive sampling, a cross sectional study was conducted at Neurology department, Mayo Hospital, Lahore. Patients fulfilling the ADA criteria for DM, and DPN were included in the study. Data was analyzed using SPSS 16 version. Results: A total of 125 patients were included in the study with 57/125 (45.6%) males and 68/125 (54.4%) females. This difference in gender based frequency was not statistically significant (p<0.324]. Although mean age of females [51.83+10.04 yrs.] was lower than that of males [53.29+9.39 yrs.] but this difference was also not significant (p<0.504). There was no significant difference (p<0.685) in the mean age at onset of DM in men (42.03+9.97yrs) and women (41.24+10.62yrs). Both genders took a mean period of 08 yrs to develop DPN. The mean age of onset of DPN was 50.87+9.43yrs in men and 49.25+10.62yrs in women and this was not statistically significant (p<0.374). Sensory-motor mixed polyneuropathy was the commonest electrophysiological pattern (51%) seen in both the genders. Conclusion: In our study, gender based differences in DPN are statistically not significant with respect to frequency of diabetes, age at diagnosis of diabetes or at onset of DPN, duration of DM before onset of DPN and electrophysiological patterns. More studies are required to settle whether gender based differences in onset and progression of diabetic neuropathy exist.

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